Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6729485 | 0.88 | CYP3A4 (0.41) | CYP3A4CYP26A1 | |
| SCHEMBL6736906 | 0.80 | RXRA (0.45) | CYP26A1 | |
| SCHEMBL7769575 | 0.77 | PPARG (0.35) | CYP3A4CYP26A1 | |
| SCHEMBL7766320 | 0.75 | CYP26B1 (0.37) | CYP3A4CYP26A1 | |
| SCHEMBL6730498 | 0.72 | CYP3A4 (0.47) | CYP3A4CYP26A1 | |
| SCHEMBL6733050 | 0.70 | CYP3A4 (0.45) | CYP3A4CYP26A1 | |
| SCHEMBL6734231 | 0.68 | CYP3A4 (0.42) | CYP3A4CYP26A1 | |
| SCHEMBL6734227 | 0.68 | CYP3A4 (0.42) | CYP3A4CYP26A1 | |
| SCHEMBL6729936 | 0.68 | CYP3A4 (0.49) | CYP3A4CYP26A1 | |
| SCHEMBL7769514 | 0.65 | RXRA (0.49) | CYP3A4CYP26A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040162339-A1 | Heterocyclic biaryl compounds, pharmaceutical and cosmetic compositions containing them and uses thereof | DIAZ PHILIPPE (FR) | 2004-08-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040162339-A1 | Heterocyclic biaryl compounds, pharmaceutical and cosmetic compositions containing them and uses thereof | TYR, MITF, CYP1B1 | CYP3A4 147/4885CYP26A1 144/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.