Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 4/20 | 0.35 |
| ▸ | CYP26A1 | O43174 | 8/20 | 0.34 |
| ▸ | CYP26B1 | Q9NR63 | 6/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.34 |
| ▸ | RXRA | P19793 | 5/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.32 |
| ▸ | RXRB | P28702 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7766320 | 0.91 | CYP26B1 (0.37) | PPARGCYP26A1CYP26B1CYP3A4RXRA | |
| SCHEMBL6729485 | 0.87 | CYP3A4 (0.41) | CYP26A1CYP26B1CYP3A4RXRARXRB | |
| SCHEMBL6736906 | 0.84 | RXRA (0.45) | CYP26A1CYP26B1RXRARXRBCNR2 | |
| SCHEMBL7770182 | 0.82 | PPARG (0.37) | PPARGCYP26A1CYP26B1CYP3A4RXRA | |
| SCHEMBL7769865 | 0.80 | RXRA (0.36) | PPARGCYP26A1CYP26B1CYP3A4RXRA | |
| SCHEMBL7770115 | 0.77 | RXRA (0.38) | PPARGCYP26A1CYP26B1CYP3A4RXRA | |
| SCHEMBL7769613 | 0.77 | RXRA (0.40) | PPARGCYP26A1CYP26B1CYP3A4RXRA | |
| SCHEMBL6730306 | 0.77 | CYP3A4 (0.33) | CYP26A1CYP3A4 | |
| SCHEMBL7773833 | 0.73 | RXRA (0.39) | PPARGCYP26A1CYP26B1CYP3A4RXRA | |
| SCHEMBL7773881 | 0.73 | CYP26B1 (0.42) | PPARGCYP26A1CYP26B1CYP3A4RXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0823903-B1 | HETEROCYCLIC DIARYL COMPOUNDS, PHARMACEUTICAL AND COSMETIC COMPOSITIONS CONTAINING SAME, AND USES THEREOF | CT INTERNAT DE RECH S (FR) | 2001-07-18 | — | — | EP | claimed |