SCHEMBL6730933

SCHEMBL6730933

CCSc1cccc(OC(F)(F)F)c1S(N)(=O)=O

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.35
HSD17B10 Q99714 1/20 0.35
PTGES2 Q9H7Z7 1/20 0.34
AR P10275 1/20 0.34
CA12 O43570 3/20 0.34
CA1 P00915 3/20 0.34
CA2 P00918 3/20 0.34
CA9 Q16790 2/20 0.34
SLC6A4 P31645 1/20 0.33
SLC6A3 Q01959 1/20 0.33
RXFP1 Q9HBX9 1/20 0.32
HSD11B1 P28845 1/20 0.32
HSD11B2 P80365 1/20 0.32
RORC P51449 2/20 0.32
KDM2B Q8NHM5 1/20 0.32
F2R P25116 1/20 0.32
DDB1 Q16531 1/20 0.32
CRBN Q96SW2 1/20 0.32
CA7 P43166 2/20 0.31
CA13 Q8N1Q1 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6727322 0.82 MAPT (0.35) ARRXFP1KDM2BF2RDDR1
SCHEMBL27466464 0.78 AR (0.32) ARRXFP1
SCHEMBL27467844 0.78 AR (0.30) AR
SCHEMBL27467845 0.76
SCHEMBL3606805 0.76 PTGES2 (0.39) PTGES2CA12CA1CA2CA9
SCHEMBL1131548 0.74 PTGES2 (0.39) PTGES2CA12CA1CA2CA9
SCHEMBL7028191 0.72 TSHR (0.46) HSD17B10CA12CA1CA2CA9
SCHEMBL6734131 0.70 MTNR1A (0.39) PTGES2CA12CA1CA2CA9
SCHEMBL7030983 0.70 ALDH1A1 (0.49) HSD17B10F2R
SCHEMBL7027818 0.69 CA1 (0.50) HSD17B10CA1CA2CA9SLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6677277-B1 Substituted sulphonyl amino(thio)carbonyl compounds and their use as herbicides BAYER AKTIENGESELLSCHAFT (DE) 2004-01-13 US disclosed
EP-0906293-B1 SUBSTITUTED SULPHONYL AMINO(THIO)CARBONYL COMPOUNDS AND THEIR USE AS HERBICIDES BAYER CROPSCIENCE AG (DE) 2003-09-17 EP disclosed