Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | ALPL | P05186 | 1/20 | 0.33 |
| ▸ | NSD2 | O96028 | 2/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | SLC22A12 | Q96S37 | 4/20 | 0.32 |
| ▸ | AR | P10275 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6730933 | 0.82 | ALOX15 (0.35) | HPGDRXFP1ARKDM2BF2R | |
| SCHEMBL6738181 | 0.79 | MAPT (0.40) | MAPTHPGDKDM4EMEN1NPC1 | |
| SCHEMBL27466464 | 0.74 | AR (0.32) | RXFP1AR | |
| SCHEMBL27467844 | 0.74 | AR (0.30) | AR | |
| SCHEMBL27467845 | 0.72 | — | — | |
| SCHEMBL6737493 | 0.72 | NSD2 (0.44) | MAPTHPGDKDM4EMEN1NPC1 | |
| SCHEMBL6735794 | 0.72 | ALPL (0.51) | MAPTHPGDKDM4EMEN1NPC1 | |
| SCHEMBL6727323 | 0.72 | SMN1; SMN2 (0.41) | MAPTHPGDKDM4EMEN1NPC1 | |
| SCHEMBL10572395 | 0.67 | SMN1; SMN2 (0.47) | MAPTHPGDKDM4EMEN1NPC1 | |
| SCHEMBL8412566 | 0.64 | HCRTR1 (0.37) | CYP2C9KDM2BF2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6677277-B1 | Substituted sulphonyl amino(thio)carbonyl compounds and their use as herbicides | BAYER AKTIENGESELLSCHAFT (DE) | 2004-01-13 | — | — | US | disclosed |
| EP-0906293-B1 | SUBSTITUTED SULPHONYL AMINO(THIO)CARBONYL COMPOUNDS AND THEIR USE AS HERBICIDES | BAYER CROPSCIENCE AG (DE) | 2003-09-17 | — | — | EP | disclosed |
| EP-0906293-A1 | SUBSTITUTED SULPHONYL AMINO(THIO)CARBONYL COMPOUNDS AND THEIR USE AS HERBICIDES | BAYER AG (DE) | 1999-04-07 | — | — | EP | disclosed |
| WO-1997046540-A1 | SUBSTITUTED SULPHONYL AMINO(THIO)CARBONYL COMPOUNDS AND THEIR USE AS HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1997-12-11 | — | — | WO | disclosed |