Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 11/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 9/20 | 0.42 |
| ▸ | AR | P10275 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | G6PD | P11413 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28636936 | 0.85 | TP53 (0.48) | TP53TDP1PDE10AESR1ESR2 | |
| SCHEMBL11592055 | 0.83 | TDP1 (0.46) | TDP1ALDH1A1MAPTHPGDMEN1 | |
| SCHEMBL135848 | 0.78 | TP53 (0.54) | TP53TDP1PDE10AESR1ESR2 | |
| SCHEMBL30058647 | 0.78 | TP53 (0.54) | TP53TDP1PDE10AESR1ESR2 | |
| SCHEMBL10624587 | 0.78 | MCL1 (0.50) | TP53TDP1KDM4EALDH1A1PKM | |
| SCHEMBL172689 | 0.76 | ALDH1A1 (0.57) | TP53TDP1PDE10AESR1ESR2 | |
| SCHEMBL28234038 | 0.75 | TP53 (0.46) | TP53TDP1PDE10AESR1ESR2 | |
| SCHEMBL370445 | 0.73 | ESR1 (0.45) | TP53TDP1PDE10AESR1ESR2 | |
| SCHEMBL23519853 | 0.71 | ALDH1A1 (0.47) | TP53TDP1PDE10AESR1ESR2 | |
| SCHEMBL3720563 | 0.71 | ALDH1A1 (0.48) | TP53TDP1PDE10AESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040249022-A1 | Method for the preparation of flameproof hermoplastic resin compositions | CHI MEI CORPORATION (TW) | 2004-12-09 | — | — | US | disclosed |