Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | SENP2 | Q9HC62 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11424324 | 0.83 | MCL1 (0.49) | MCL1KMT2ASMN1; SMN2MEN1PKM | |
| SCHEMBL11652637 | 0.81 | HSP90AA1 (0.48) | KMT2ASMN1; SMN2MEN1ALDH1A1TP53 | |
| SCHEMBL11592055 | 0.81 | TDP1 (0.46) | KMT2ASMN1; SMN2MEN1POLBNPC1 | |
| SCHEMBL6731103 | 0.78 | TP53 (0.46) | KMT2AMEN1PKMNPC1ALDH1A1 | |
| SCHEMBL6564428 | 0.76 | KDM4E (0.56) | MCL1KMT2ASMN1; SMN2MEN1PKM | |
| SCHEMBL18116612 | 0.76 | MCL1 (0.64) | MCL1KMT2ASMN1; SMN2MEN1PKM | |
| SCHEMBL130126 | 0.74 | MCL1 (0.52) | MCL1KMT2ASMN1; SMN2MEN1PKM | |
| SCHEMBL11087092 | 0.72 | KMT2A (0.50) | MCL1KMT2ASMN1; SMN2MEN1PKM | |
| SCHEMBL3757525 | 0.72 | MCL1 (0.50) | MCL1KMT2ASMN1; SMN2MEN1PKM | |
| SCHEMBL882328 | 0.72 | MCL1 (0.50) | MCL1KMT2ASMN1; SMN2MEN1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4734517-A | HERBICIDES | MONSANTO COMPANY (US) | 1988-03-29 | — | — | US | disclosed |
| EP-0141794-A1 | Aralower alkyl and substituted aralower alkyl esters of N-phosphonomethylglycines | Monsanto Company (US) | 1985-05-15 | — | — | EP | disclosed |
| US-4120689-A | POSTEMERGENT | MONSANTO COMPANY (US) | 1978-10-17 | — | — | US | disclosed |