Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16508363 | 0.86 | TDP1 (0.46) | TDP1SMN1; SMN2L3MBTL1KMT2ALMNA | |
| SCHEMBL6731103 | 0.83 | TP53 (0.46) | TDP1KMT2ANPC1HPGDMEN1 | |
| SCHEMBL11586044 | 0.81 | TDP1 (0.44) | TDP1SMN1; SMN2L3MBTL1KMT2ALMNA | |
| SCHEMBL10624587 | 0.81 | MCL1 (0.50) | TDP1SMN1; SMN2KMT2ANPC1MEN1 | |
| SCHEMBL25671816 | 0.74 | TDP1 (0.39) | TDP1SMN1; SMN2L3MBTL1KMT2ALMNA | |
| SCHEMBL11652339 | 0.74 | TSHR (0.50) | SMN1; SMN2L3MBTL1KMT2ALMNANPC1 | |
| SCHEMBL11652347 | 0.74 | TSHR (0.50) | SMN1; SMN2L3MBTL1KMT2ALMNANPC1 | |
| SCHEMBL2288471 | 0.73 | TDP1 (0.50) | TDP1SMN1; SMN2L3MBTL1KMT2ALMNA | |
| SCHEMBL258227 | 0.73 | ACHE (0.48) | TDP1SMN1; SMN2L3MBTL1KMT2ALMNA | |
| SCHEMBL4859496 | 0.73 | TDP1 (0.46) | TDP1SMN1; SMN2L3MBTL1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4083898-A | Process for preparing O-aryl, N-phosphonomethylglycinonitriles | MONSANTO COMPANY (US) | 1978-04-11 | — | — | US | claimed |
| US-4120689-A | POSTEMERGENT | MONSANTO COMPANY (US) | 1978-10-17 | — | — | US | disclosed |
| US-4089671-A | HERBICIDES | MONSANTO COMPANY (US) | 1978-05-16 | — | — | US | disclosed |
| US-4083898-A | Process for preparing O-aryl, N-phosphonomethylglycinonitriles | MONSANTO COMPANY (US) | 1978-04-11 | — | — | US | disclosed |
| US-4067719-A | O-Aryl N-phosphonomethylglycinonitriles and the herbicidal use thereof | MONSANTO COMPANY (US) | 1978-01-10 | — | — | US | disclosed |