SCHEMBL673184

SCHEMBL673184

CCCCCCCCNC(=O)c1coc(C2CCCN2C(=O)OCc2ccccc2)n1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PRCP P42785 1/20 0.56
TBXA2R P21731 5/20 0.49
PTGER1 P34995 1/20 0.48
PTGER4 P35408 1/20 0.48
PTGFR P43088 1/20 0.48
PTGER3 P43115 1/20 0.48
PTGER2 P43116 1/20 0.48
PTGIR P43119 1/20 0.48
PTGDR Q13258 1/20 0.48
AADAT Q8N5Z0 2/20 0.44
TMEM97 Q5BJF2 2/20 0.44
SIGMAR1 Q99720 2/20 0.44
ELANE P08246 1/20 0.43
HSD17B10 Q99714 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.41
TSHR P16473 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
KDM4E B2RXH2 1/20 0.41
LMNA P02545 1/20 0.41
EPHX2 P34913 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15759813 1.00 PRCP (0.56) PRCPTBXA2RPTGER1PTGER4PTGFR
SCHEMBL673185 1.00 PRCP (0.56) PRCPTBXA2RPTGER1PTGER4PTGFR
SCHEMBL475407 0.83 AADAT (0.51) AADATTMEM97SIGMAR1HSD17B10TSHR
SCHEMBL475406 0.83 AADAT (0.51) AADATTMEM97SIGMAR1HSD17B10TSHR
SCHEMBL953139 0.81 AADAT (0.52) AADATTMEM97SIGMAR1HSD17B10
SCHEMBL953138 0.81 AADAT (0.52) AADATTMEM97SIGMAR1HSD17B10
SCHEMBL672507 0.77 PRCP (0.61) PRCPTMEM97SIGMAR1ELANEHSD17B10
SCHEMBL672508 0.77 PRCP (0.61) PRCPTMEM97SIGMAR1ELANEHSD17B10
SCHEMBL18850754 0.77 HCRTR1 (0.53) AADATTMEM97SIGMAR1HSD17B10
SCHEMBL11331803 0.76 PRCP (0.89) PRCPHSD17B10SMN1; SMN2TSHRL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9422273-B2 Compounds act at multiple prostaglandin receptors giving a general anti-inflammatory response ALLERGAN, INC. (US) 2016-08-23 US disclosed
US-9422273-B2 Compounds act at multiple prostaglandin receptors giving a general anti-inflammatory response ALLERGAN, INC. (US) 2016-08-23 US disclosed
US-9422273-B2 Compounds act at multiple prostaglandin receptors giving a general anti-inflammatory response ALLERGAN, INC. (US) 2016-08-23 US disclosed
US-20160068520-A1 COMPOUNDS ACT AT MULTIPLE PROSTAGLANDIN RECEPTORS GIVING A GENERAL ANTI-INFLAMMATORY RESPONSE ALLERGAN, INC. 2016-03-10 US disclosed
US-20160068520-A1 COMPOUNDS ACT AT MULTIPLE PROSTAGLANDIN RECEPTORS GIVING A GENERAL ANTI-INFLAMMATORY RESPONSE ALLERGAN, INC. 2016-03-10 US disclosed
US-20160068520-A1 COMPOUNDS ACT AT MULTIPLE PROSTAGLANDIN RECEPTORS GIVING A GENERAL ANTI-INFLAMMATORY RESPONSE ALLERGAN, INC. 2016-03-10 US disclosed
US-9085567-B2 Compounds act at multiple prostaglandin receptors giving a general anti-inflammatory response ALLERGAN, INC. (US) 2015-07-21 US disclosed
US-9085567-B2 Compounds act at multiple prostaglandin receptors giving a general anti-inflammatory response ALLERGAN, INC. (US) 2015-07-21 US disclosed
US-9085567-B2 Compounds act at multiple prostaglandin receptors giving a general anti-inflammatory response ALLERGAN, INC. (US) 2015-07-21 US disclosed
US-20140249192-A1 COMPOUNDS ACT AT MULTIPLE PROSTAGLANDIN RECEPTORS GIVING A GENERAL ANTI-INFLAMMATORY RESPONSE ALLERGAN, INC. (US) 2014-09-04 US disclosed
US-20130150417-A1 COMPOUNDS ACT AT MULTIPLE PROSTAGLANDIN RECEPTORS GIVING A GENERAL ANTI-INFLAMMATORY RESPONSE ALLERGAN, INC. (US) 2013-06-13 US disclosed
WO-2012145737-A1 FATTY ACID AMIDE HYDROLASE INHIBITORS FOR TREATING ALLERGAN, INC. (US) 2012-10-26 WO disclosed
US-20120270915-A1 FATTY ACID AMIDE HYDROLASE INHIHIBITORS FOR TREATING PAIN ENERGY, UNITED STATES DEPARTMENT OF 2012-10-25 US disclosed
US-20120270915-A1 FATTY ACID AMIDE HYDROLASE INHIHIBITORS FOR TREATING PAIN ENERGY, UNITED STATES DEPARTMENT OF 2012-10-25 US disclosed
US-20120270915-A1 FATTY ACID AMIDE HYDROLASE INHIHIBITORS FOR TREATING PAIN ENERGY, UNITED STATES DEPARTMENT OF 2012-10-25 US disclosed
US-20120077858-A1 COMPOUNDS ACT AT MULTIPLE PROSTAGLANDIN RECEPTORS GIVING A GENERAL ANTI-INFLAMMATORY RESPONSE ALLERGAN, INC. (US) 2012-03-29 US disclosed
US-20120077858-A1 COMPOUNDS ACT AT MULTIPLE PROSTAGLANDIN RECEPTORS GIVING A GENERAL ANTI-INFLAMMATORY RESPONSE ALLERGAN, INC. (US) 2012-03-29 US disclosed
US-20120077858-A1 COMPOUNDS ACT AT MULTIPLE PROSTAGLANDIN RECEPTORS GIVING A GENERAL ANTI-INFLAMMATORY RESPONSE ALLERGAN, INC. (US) 2012-03-29 US disclosed
WO-2012024559-A1 COMPOUNDS ACT AT MULTIPLE PROSTAGLANDIN RECEPTORS GIVING A GENERAL ANTI-INFLAMMATORY RESPONSE ALLERGAN, INC. (US) 2012-02-23 WO disclosed
WO-2012024559-A1 COMPOUNDS ACT AT MULTIPLE PROSTAGLANDIN RECEPTORS GIVING A GENERAL ANTI-INFLAMMATORY RESPONSE ALLERGAN, INC. (US) 2012-02-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120077858-A1 COMPOUNDS ACT AT MULTIPLE PROSTAGLANDIN RECEPTORS GIVING A GENERAL ANTI-INFLAMMATORY RESPONSE PTGER1, PTGER4, PTGER3 PRCP 2972/4885TBXA2R 17/4885PTGER1 1/4885
US-20120270915-A1 FATTY ACID AMIDE HYDROLASE INHIHIBITORS FOR TREATING PAIN FAAH, FAAH2, FAH PRCP 3383/4885TBXA2R 143/4885PTGER1 26/4885
US-20130150417-A1 COMPOUNDS ACT AT MULTIPLE PROSTAGLANDIN RECEPTORS GIVING A GENERAL ANTI-INFLAMMATORY RESPONSE PTGER1, PTGER4, PTGER3 PRCP 1704/4885TBXA2R 12/4885PTGER1 1/4885
US-20160068520-A1 COMPOUNDS ACT AT MULTIPLE PROSTAGLANDIN RECEPTORS GIVING A GENERAL ANTI-INFLAMMATORY RESPONSE PTGER1, PTGER4, PTGER3 PRCP 2972/4885TBXA2R 17/4885PTGER1 1/4885
US-20140249192-A1 COMPOUNDS ACT AT MULTIPLE PROSTAGLANDIN RECEPTORS GIVING A GENERAL ANTI-INFLAMMATORY RESPONSE PTGER1, PTGER4, PTGER3 PRCP 2972/4885TBXA2R 17/4885PTGER1 1/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.