Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.50 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.46 |
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
| ▸ | MAP3K8 | P41279 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.41 |
| ▸ | EIF2AK2 | P19525 | 1/20 | 0.41 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.41 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6736390 | 0.86 | MEN1 (0.50) | MEN1KMT2AMAPTPABPC1CYP19A1 | |
| SCHEMBL6733124 | 0.82 | MAPT (0.59) | MEN1KMT2AMAPTPABPC1ALDH1A1 | |
| SCHEMBL6732917 | 0.76 | LTA4H (0.56) | MEN1KMT2AMAPTPABPC1ALDH1A1 | |
| SCHEMBL6731979 | 0.76 | LTA4H (0.56) | MEN1KMT2AMAPTPABPC1ALDH1A1 | |
| SCHEMBL6735252 | 0.75 | MEN1 (0.52) | MEN1KMT2AMAPTPABPC1CYP19A1 | |
| SCHEMBL6735876 | 0.75 | MAPK14 (0.68) | MEN1KMT2AMAPTCYP19A1ALDH1A1 | |
| SCHEMBL6732732 | 0.74 | LTA4H (0.57) | MEN1KMT2AMAPTPABPC1ALDH1A1 | |
| SCHEMBL6731984 | 0.74 | ALDH1A1 (0.50) | CYP19A1ALDH1A1SMN1; SMN2MAP3K8TDP1 | |
| SCHEMBL19312422 | 0.72 | LTA4H (0.60) | MEN1KMT2AMAPTPABPC1ALDH1A1 | |
| SCHEMBL6732463 | 0.72 | CYP2C19 (0.62) | MEN1KMT2AMAPTPABPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6800651-B2 | Potentiators of glutamate receptors | ELI LILLY AND COMPANY | 2004-10-05 | — | — | US | disclosed |
| US-20040006114-A1 | Potentiators of glutamate receptors | ELI LILLY AND COMPANY | 2004-01-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040006114-A1 | Potentiators of glutamate receptors | GRM1, GRIN1, GRM2 | MEN1 2793/4885KMT2A 3440/4885MAPT 3885/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.