SCHEMBL6732154

SCHEMBL6732154

C=CC[SiH](C)[Hf](Cl)(Cl)(C1C=Cc2ccccc21)C1C=Cc2ccccc21

nearest known ligand 0.33

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
HTR6 P50406 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6731811 0.86 HTR6 (0.31) HTR6
SCHEMBL6720596 0.81
SCHEMBL216950 0.79 HTR6 (0.33) HTR6
SCHEMBL6723239 0.78 HTR6 (0.30) HTR6
SCHEMBL6727351 0.77 HTR6 (0.32) HTR6
SCHEMBL6469811 0.75 HTR2A (0.33) HTR6
SCHEMBL216943 0.74 SIGMAR1 (0.31)
SCHEMBL6916191 0.71
SCHEMBL7106720 0.70
SCHEMBL7107274 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6746981-B2 OLEFIN POLYMERIZATION CATALYSTS WITH PRODUCTIVITY WHEN FRESH OF >/= 18,000 GRAMS OF POLYETHYLENE PER GRAM OF CATALYST IN ONE HOUR, AND A SPECIFIC SURFACE AREA OF </= 20 M2/G ALBEMARLE CORPORATION 2004-06-08 US disclosed
US-6730758-B2 ADDITION POLYMERIZATION OF ALPHA-OLEFIN HYDROCARBON IN PRESENCE OF SELF-SUPPORTED VINYLOLEFIN-PREPOLYMERIZED CATALYST ALBEMARLE CORPORATION 2004-05-04 US disclosed
EP-1037931-B1 CATALYST COMPOSITIONS OF ENHANCED PRODUCTIVITY ALBEMARLE CORP (US) 2004-02-04 EP disclosed
US-6677265-B1 THE METALLOCENE USED AS THE FEED HAVING IN THE MOLECULE AT LEAST ONE POLYMERIZABLE OLEFINIC SUBSTITUENT ALBEMARLE CORPORATION 2004-01-13 US disclosed
US-20030191254-A1 PARTICULATE GROUP 4 METALLOCENE-ALUMINOXANE CATALYST COMPOSITIONS DEVOID OF PREFORMED SUPPORT, AND THEIR PREPARATION AND THEIR USE ALBEMARLE CORPORATION 2003-10-09 US disclosed
US-20030105253-A1 Particulate group 4 metallocene-aluminoxane catalyst compositions devoid of preformed support, and their preparation and their use ALBEMARLE CORPORATION 2003-06-05 US disclosed
US-6551955-B1 Olefin polymerization catalysts; efficiency ALBEMARLE CORPORATION 2003-04-22 US disclosed
US-6521728-B1 Particulate group 4 metallocene-aluminoxane catalyst compositions devoid of preformed support, and their preparation and their use ALBEMARLE CORPORATION 2003-02-18 US disclosed
WO-2001098374-A2 PROCESS OF PRODUCING SELF-SUPPORTED CATALYSTS ALBEMARLE CORPORATION (US) 2001-12-27 WO disclosed
WO-2001098381-A2 POLYMERIZATION PROCESS USING SELF-SUPPORTED CATALYSTS ALBEMARLE CORPORATION (US) 2001-12-27 WO disclosed
WO-2001098380-A2 PARTICULATE GROUP 4 METALLOCENE-ALUMINOXANE CATALYST COMPOSITIONS DEVOID OF PREFORMED SUPPORT, AND THEIR PREPARATION AND THEIR USE ALBEMARLE CORPORATION (US) 2001-12-27 WO disclosed
US-6294496-B1 VERY HIGH PRODUCTIVITIES; PREPOLYMERIZING VINYLOLEFIN WITH A GROUP 4 METALLOCENE-ALUMINOXANE SOLUTION ALBEMARLE CORPORATION 2001-09-25 US disclosed
EP-1037931-A1 CATALYST COMPOSITIONS OF ENHANCED PRODUCTIVITY ALBEMARLE CORPORATION (US) 2000-09-27 EP disclosed
WO-1999029738-A1 CATALYST COMPOSITIONS OF ENHANCED PRODUCTIVITY ALBEMARLE CORPORATION (US) 1999-06-17 WO disclosed