Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLO1 | Q04760 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | CES2 | O00748 | 3/20 | 0.34 |
| ▸ | ACHE | P22303 | 3/20 | 0.34 |
| ▸ | CES1 | P23141 | 3/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6732281 | 1.00 | GLO1 (0.41) | GLO1ALOX15ALDH1A1LMNAHSD17B10 | |
| SCHEMBL10820989 | 0.86 | GLO1 (0.39) | GLO1ALOX15ALDH1A1LMNAHSD17B10 | |
| SCHEMBL10820990 | 0.86 | GLO1 (0.39) | GLO1ALOX15ALDH1A1LMNAHSD17B10 | |
| SCHEMBL10364778 | 0.84 | ALOX15 (0.39) | GLO1ALOX15ALDH1A1CYP1A2MEN1 | |
| SCHEMBL10364776 | 0.84 | ALOX15 (0.39) | GLO1ALOX15ALDH1A1CYP1A2MEN1 | |
| SCHEMBL10820971 | 0.81 | GLO1 (0.41) | GLO1ALOX15ALDH1A1LMNAHSD17B10 | |
| SCHEMBL18456945 | 0.81 | GLO1 (0.41) | GLO1ALOX15ALDH1A1LMNAHSD17B10 | |
| SCHEMBL10820970 | 0.81 | GLO1 (0.41) | GLO1ALOX15ALDH1A1LMNAHSD17B10 | |
| SCHEMBL9653470 | 0.81 | ALOX15 (0.43) | GLO1ALOX15ALDH1A1LMNAHSD17B10 | |
| SCHEMBL3158392 | 0.81 | ALOX15 (0.43) | GLO1ALOX15ALDH1A1LMNAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014126580-A1 | PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO | DOW AGROSCIENCES LLC (US) | 2014-08-21 | — | — | WO | disclosed |
| WO-2013106254-A1 | PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO | DOW AGROSCIENCES LLC (US) | 2013-07-18 | — | — | WO | disclosed |
| US-20040220231-A1 | Substituted pyridines useful for inhibiting cholesteryl ester transfer protein activity | LEE LEN F (US) | 2004-11-04 | — | — | US | disclosed |
| US-6794396-B2 | Substituted pyridines useful for inhibiting cholesteryl ester transfer protein activity | PHARMACIA CORPORATION | 2004-09-21 | — | — | US | disclosed |
| US-20040038939-A1 | Substituted pyridines useful for inhibiting cholesteryl ester transfer protein activity | PHARMACIA CORPORATION | 2004-02-26 | — | — | US | disclosed |
| US-6605624-B1 | Preventing and/or treating atherosclerosis and other coronary artery diseases | PHARMACIA CORPORATION | 2003-08-12 | — | — | US | disclosed |
| US-5196045-A | Substituted pyridine herbicides | MONSANTO COMPANY (US) | 1993-03-23 | — | — | US | disclosed |
| EP-0252055-B1 | SUBSTITUTED PYRIDINE HERBICIDES | Monsanto Company (US) | 1992-01-22 | — | — | EP | disclosed |
| US-5019153-A | Substituted pyridine herbicides | MONSANTO COMPANY (US) | 1991-05-28 | — | — | US | disclosed |
| EP-0181852-B1 | SUBSTITUTED 2,6-SUBSTITUTED PYRIDINE COMPOUNDS | Monsanto Company (US) | 1990-08-29 | — | — | EP | disclosed |
| EP-0182769-B1 | 2,6-SUBSTITUTED PYRIDINE COMPOUNDS | Monsanto Company (US) | 1990-08-01 | — | — | EP | disclosed |
| US-4921530-A | Certain 3,5-pyridine dicarboxylates, their thio analogues having herbicidal activity | MONSANTO COMPANY (US) | 1990-05-01 | — | — | US | disclosed |
| US-4885026-A | FLUORINE-CONTAINING METHYL GROUP AT THE 2- OR 6-POSITION; PRE- AND POSTEMERGENT | MONSANTO COMPANY (US) | 1989-12-05 | — | — | US | disclosed |
| US-4835279-A | 2,6-substituted pyridine compounds | MONSANTO COMPANY (US) | 1989-05-30 | — | — | US | disclosed |
| US-4797149-A | HERBICIDES | MONSANTO COMPANY (US) | 1989-01-10 | — | — | US | disclosed |
| EP-0252055-A1 | Substituted pyridine herbicides | Monsanto Company (US) | 1988-01-07 | — | — | EP | disclosed |
| US-4698093-A | POST, PRE EMERGENTS | MONSANTO COMPANY (US) | 1987-10-06 | — | — | US | disclosed |
| US-4655816-A | PLANT GROWTH REGULATORS | MONSANTO COMPANY (US) | 1987-04-07 | — | — | US | disclosed |
| EP-0182769-A1 | 2,6-Substituted pyridine compounds | Monsanto Company (US) | 1986-05-28 | — | — | EP | disclosed |
| EP-0181852-A1 | Substituted 2,6-substituted pyridine compounds | Monsanto Company (US) | 1986-05-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040038939-A1 | Substituted pyridines useful for inhibiting cholesteryl ester transfer protein activity | CETP, CES1, MTTP | GLO1 1210/4885ALOX15 3178/4885ALDH1A1 1154/4885 |
| US-20040220231-A1 | Substituted pyridines useful for inhibiting cholesteryl ester transfer protein activity | CETP, MTTP, LCAT | GLO1 1324/4885ALOX15 3254/4885ALDH1A1 1364/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.