Sugi Predict

Sugi Predict / Compounds / SCHEMBL3158392

SCHEMBL3158392

SCHEMBL3158392

CCOC(=O)/C(C)=C(\N)C(F)(F)F

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALOX15 P16050 1/20 0.43
▸ GLO1 Q04760 1/20 0.39
▸ ALDH1A1 P00352 3/20 0.39
▸ LMNA P02545 1/20 0.39
▸ HSD17B10 Q99714 1/20 0.39
▸ MAPT P10636 1/20 0.36
▸ CES2 O00748 4/20 0.36
▸ ACHE P22303 4/20 0.36
▸ CES1 P23141 4/20 0.36
▸ NPSR1 Q6W5P4 2/20 0.35
▸ TSHR P16473 1/20 0.34
▸ HDAC4 P56524 2/20 0.34
▸ HDAC6 Q9UBN7 2/20 0.34
▸ HDAC3 O15379 1/20 0.34
▸ HDAC1 Q13547 1/20 0.34
▸ HPGD P15428 1/20 0.34
▸ MGAM O43451 1/20 0.33
▸ GAA P10253 1/20 0.33
▸ SI P14410 1/20 0.33
▸ MGAM2 Q2M2H8 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3158398 1.00 ALOX15 (0.43) ALOX15GLO1ALDH1A1LMNAHSD17B10
SCHEMBL9653474 0.84 ALOX15 (0.43) ALOX15GLO1ALDH1A1LMNAHSD17B10
SCHEMBL9653470 0.84 ALOX15 (0.43) ALOX15GLO1ALDH1A1LMNAHSD17B10
SCHEMBL578450 0.82 ALOX15 (0.44) ALOX15GLO1ALDH1A1LMNAHSD17B10
SCHEMBL6732281 0.81 GLO1 (0.41) ALOX15GLO1ALDH1A1LMNAHSD17B10
SCHEMBL6732284 0.81 GLO1 (0.41) ALOX15GLO1ALDH1A1LMNAHSD17B10
SCHEMBL22572749 0.80 ALOX15 (0.43) ALOX15GLO1ALDH1A1LMNAHSD17B10
SCHEMBL22912550 0.80 ALOX15 (0.43) ALOX15GLO1ALDH1A1LMNAHSD17B10
SCHEMBL28324138 0.79 THRB (0.37) ALOX15GLO1ALDH1A1LMNAHSD17B10
SCHEMBL1144348 0.76 ALOX15 (0.52) ALOX15GLO1ALDH1A1LMNAHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5919732-A Herbicidal 3-arylamino-6-trifluoromethyluracils HOECHST SCHERING AGREVO GMBH (DE) 1999-07-06 — — US claimed
WO-1998034924-A1 HERBICIDAL 3-ARYLAMINO-6-TRIFLUOROMETHYL URACYLS HOECHST SCHERING AGREVO GMBH (DE) 1998-08-13 — — WO claimed
US-12133529-B2 Herbicidal phenylethers BASF SE (DE) 2024-11-05 — — US disclosed
US-20230345941-A1 HERBICIDAL PHENYLETHERS BASF SE (DE) 2023-11-02 — — US disclosed
US-20230345941-A1 HERBICIDAL PHENYLETHERS BASF SE (DE) 2023-11-02 — — US disclosed
US-20230131260-A1 SUBSTITUTED THIOPHENYL URACILS, SALTS THEREOF AND THE USE THEREOF AS HERBICIDAL AGENTS SYNGENTA CROP PROTECTION AG (CH) 2023-04-27 — — US disclosed
US-20230131260-A1 SUBSTITUTED THIOPHENYL URACILS, SALTS THEREOF AND THE USE THEREOF AS HERBICIDAL AGENTS SYNGENTA CROP PROTECTION AG (CH) 2023-04-27 — — US disclosed
US-20230131260-A1 SUBSTITUTED THIOPHENYL URACILS, SALTS THEREOF AND THE USE THEREOF AS HERBICIDAL AGENTS SYNGENTA CROP PROTECTION AG (CH) 2023-04-27 — — US disclosed
US-11497212-B2 Substituted thiophenyl uracils, salts thereof and the use thereof as herbicidal agents SYNGENTA CROP PROTECTION AG (CH) 2022-11-15 — — US disclosed
US-11274083-B2 Substituted thiophenyl uracils, salts thereof and the use thereof as herbicidal agents SYNGENTA CROP PROTECTION AG (CH) 2022-03-15 — — US disclosed
EP-3728237-B1 SUBSTITUTED THIOPHENYLURACILS , THEIR SALTS AND USE OF SAID COMPOUNDS AS HERBICIDAL AGENTS SYNGENTA CROP PROTECTION AG (CH) 2022-02-09 — — EP disclosed
US-5777154-A Method for preparing 3-amino substituted crotonates ROHM AND HAAS COMPANY (US) 1998-07-07 — — US disclosed
EP-0808826-A1 A method for preparing 3-amino substituted crotonates ROHM AND HAAS COMPANY (US) 1997-11-26 — — EP disclosed
EP-0769495-A1 Fungicides ZENECA LIMITED (GB) 1997-04-23 — — EP disclosed
US-5532208-A HERBICIDES SUMITOMO CHEMICAL CO., LTD. (JP) 1996-07-02 — — US disclosed
WO-1995017096-A1 HERBICIDAL HALOALKYLURACILS FMC CORPORATION (US) 1995-06-29 — — WO disclosed
US-5399543-A Chemical intermediates for the herbicides also claimed. FMC CORPORATION (US) 1995-03-21 — — US disclosed
US-5366955-A HERBICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1994-11-22 — — US disclosed
EP-0568041-A1 Pyrimidone derivatives and their use SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1993-11-03 — — EP disclosed
US-5232898-A Herbicides CIBA-GEIGY CORPORATION (US) 1993-08-03 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11497212-B2 Substituted thiophenyl uracils, salts thereof and the use thereof as herbicidal agents UNG, TYMP, TYMS ALOX15 2905/4885GLO1 55/4885ALDH1A1 170/4885
US-11274083-B2 Substituted thiophenyl uracils, salts thereof and the use thereof as herbicidal agents UNG, TYMP, TYMS ALOX15 2689/4885GLO1 51/4885ALDH1A1 133/4885
US-12133529-B2 Herbicidal phenylethers DDT, HPD, GSTM2 ALOX15 2239/4885GLO1 69/4885ALDH1A1 35/4885
US-20230345941-A1 HERBICIDAL PHENYLETHERS DDT, HPD, GSTM2 ALOX15 2239/4885GLO1 69/4885ALDH1A1 35/4885
US-20230131260-A1 SUBSTITUTED THIOPHENYL URACILS, SALTS THEREOF AND THE USE THEREOF AS HERBICIDAL AGENTS UNG, TYMP, TYMS ALOX15 2905/4885GLO1 55/4885ALDH1A1 170/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.