Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.71 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.71 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.71 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Disulfoton SCHEMBL27180 | 0.84 | ALDH1A1 (1.00) | ALDH1A1HSD17B10CYP3A4MEN1KMT2A | |
| Disulfoton SCHEMBL6732289 | 0.84 | ALDH1A1 (1.00) | ALDH1A1HSD17B10CYP3A4MEN1KMT2A | |
| Disulfoton SCHEMBL7610063 | 0.84 | ALDH1A1 (1.00) | ALDH1A1HSD17B10CYP3A4MEN1KMT2A | |
| SCHEMBL10109441 | 0.82 | ALDH1A1 (0.52) | ALDH1A1HSD17B10CYP3A4MEN1KMT2A | |
| Ethion SCHEMBL4108994 | 0.80 | ALDH1A1 (0.92) | ALDH1A1HSD17B10CYP3A4MEN1KMT2A | |
| Disulfoton SCHEMBL8932165 | 0.79 | ALDH1A1 (0.89) | ALDH1A1HSD17B10CYP3A4MEN1KMT2A | |
| SCHEMBL29350865 | 0.79 | ALDH1A1 (0.81) | ALDH1A1HSD17B10CYP3A4MEN1KMT2A | |
| Demeton S SCHEMBL8660394 | 0.75 | ALDH1A1 (0.79) | ALDH1A1HSD17B10CYP3A4MEN1KMT2A | |
| Disulfoton SCHEMBL8669947 | 0.73 | ALDH1A1 (0.77) | ALDH1A1HSD17B10CYP3A4MEN1KMT2A | |
| SCHEMBL8535140 | 0.73 | ALDH1A1 (0.78) | ALDH1A1HSD17B10CYP3A4MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8865683-B2 | Active compound combinations having insecticidal properties | BAYER CROPSCIENCE AG (DE) | 2014-10-21 | — | — | US | disclosed |
| US-8846567-B2 | Active compound combinations having insecticidal and acaricidal properties | BAYER CROPSCIENCE AG (DE) | 2014-09-30 | — | — | US | disclosed |
| US-20120021901-A1 | Active Compound Combinations Having Insecticidal and Acaricidal Properties | BAYER CROPSCIENCE AG (DE) | 2012-01-26 | — | — | US | disclosed |
| US-20100249070-A1 | Active Compound Combinations Having Insecticidal Properties | BAYER CROPSCIENCE AG (DE) | 2010-09-30 | — | — | US | disclosed |
| US-20090318386-A1 | ACTIVE COMPOUND COMBINATIONS HAVING INSECTICIDAL AND ACARICIDAL PROPERTIES | FISCHER REINER | 2009-12-24 | — | — | US | disclosed |
| US-20080293676-A1 | Insecticidal Agents Based on Selected Insecticides and Safeners | BAYER CROPSCIENCE AG (DE) | 2008-11-27 | — | — | US | disclosed |
| US-20070142327-A1 | Active compound combinations having insecticidal properties | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2007-06-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070142327-A1 | Active compound combinations having insecticidal properties | ACHE, ANTXR2, NANP | ALDH1A1 4054/4885HSD17B10 3280/4885CYP3A4 1585/4885 |
| US-20090318386-A1 | ACTIVE COMPOUND COMBINATIONS HAVING INSECTICIDAL AND ACARICIDAL PROPERTIES | AADAC, ACAA2, CYP51A1 | ALDH1A1 1437/4885HSD17B10 126/4885CYP3A4 716/4885 |
| US-20100249070-A1 | Active Compound Combinations Having Insecticidal Properties | ACHE, AADAC, NANP | ALDH1A1 4083/4885HSD17B10 3436/4885CYP3A4 1408/4885 |
| US-20120021901-A1 | Active Compound Combinations Having Insecticidal and Acaricidal Properties | ACHE, DDT, BCHE | ALDH1A1 424/4885HSD17B10 1528/4885CYP3A4 279/4885 |
| US-20080293676-A1 | Insecticidal Agents Based on Selected Insecticides and Safeners | ACHE, NCS1, HCN1 | ALDH1A1 1640/4885HSD17B10 570/4885CYP3A4 1115/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.