Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCAT2 | O15382 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.41 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.41 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.41 |
| ▸ | GRM5 | P41594 | 1/20 | 0.41 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.40 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.38 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.36 |
| ▸ | METAP2 | P50579 | 1/20 | 0.36 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.36 |
| ▸ | FEN1 | P39748 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11776499 | 0.94 | BCAT2 (0.53) | BCAT2RAB9ANPC1CSNK1A1TYRO3 | |
| SCHEMBL11525911 | 0.79 | RAB9A (0.45) | BCAT2RAB9ANPC1KDM4EALDH1A1 | |
| SCHEMBL31012518 | 0.77 | BCAT2 (0.71) | BCAT2RAB9ANPC1CSNK1A1TYRO3 | |
| SCHEMBL1110181 | 0.77 | BCAT2 (0.71) | BCAT2RAB9ANPC1CSNK1A1TYRO3 | |
| SCHEMBL210767 | 0.75 | BCAT2 (0.74) | BCAT2RAB9ANPC1CSNK1A1TYRO3 | |
| SCHEMBL30514077 | 0.75 | BCAT2 (0.74) | BCAT2RAB9ANPC1CSNK1A1TYRO3 | |
| SCHEMBL673264 | 0.75 | BCAT2 (0.46) | BCAT2RAB9ANPC1ALDH1A1PARP1 | |
| Hydrochloric Acid SCHEMBL16463881 | 0.73 | BCAT2 (0.71) | BCAT2RAB9ANPC1CSNK1A1TYRO3 | |
| SCHEMBL2200428 | 0.73 | GPR55 (0.38) | BCAT2RAB9ANPC1ALDH1A1MAPT | |
| SCHEMBL28555590 | 0.72 | GRM5 (0.61) | BCAT2CSNK1A1TYRO3DYRK1BGRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150190504-A1 | WOUND HEALING | KINETIC CONCEPTS, INC. | 2015-07-09 | — | — | US | disclosed |
| US-8957076-B2 | Wound healing | SYSTAGENIX WOUND MANAGEMENT (US), INC. (US) | 2015-02-17 | — | — | US | disclosed |
| US-8063052-B2 | Wound healing | SYSTAGENIX WOUND MANAGEMENT (US), INC. (US) | 2011-11-22 | — | — | US | disclosed |
| US-20100099622-A1 | WOUND HEALING | SYSTAGENIX WOUND MANAGEMENT (US), INC. (US) | 2010-04-22 | — | — | US | disclosed |
| US-20090170910-A1 | WOUND HEALING | KCI USA, INC. | 2009-07-02 | — | — | US | disclosed |
| EP-1786409-A1 | WOUND HEALING | ETHICON, INC. (US) | 2007-05-23 | — | — | EP | disclosed |
| WO-2006028836-A1 | WOUND HEALING | ETHICON, INC. (US) | 2006-03-16 | — | — | WO | disclosed |
| US-20050065195-A1 | Oxadiazolyl-biphenylcarboxamides and their use as p38 kinase inhibitors | GLAXO GROUP LIMITED (GB) | 2005-03-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050065195-A1 | Oxadiazolyl-biphenylcarboxamides and their use as p38 kinase inhibitors | MAPK3, MAPK1, MAPKAPK3 | BCAT2 1158/4885RAB9A 2857/4885NPC1 2844/4885 |
| US-20100099622-A1 | WOUND HEALING | MAPK1, MAPK3, MAPK4 | BCAT2 2070/4885RAB9A 1287/4885NPC1 4100/4885 |
| US-20090170910-A1 | WOUND HEALING | MAPK1, MAPK3, MAPK4 | BCAT2 2070/4885RAB9A 1287/4885NPC1 4100/4885 |
| US-20150190504-A1 | WOUND HEALING | MAPK1, MAPK3, MAPK4 | BCAT2 2070/4885RAB9A 1287/4885NPC1 4100/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.