Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 6/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.37 |
| ▸ | APP | P05067 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | DDO | Q99489 | 1/20 | 0.36 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.35 |
| ▸ | P4HA1 | P13674 | 2/20 | 0.34 |
| ▸ | P4HTM | Q9NXG6 | 2/20 | 0.34 |
| ▸ | TPMT | P51580 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL410293 | 0.84 | KMT2A (0.45) | HCAR2ALDH1A1KDM4EKMT2ACYP2C9 | |
| SCHEMBL106575 | 0.79 | — | — | |
| Methylamine SCHEMBL27659538 | 0.78 | HCAR2 (0.85) | HCAR2ALDH1A1KDM4EALOX15HSD17B10 | |
| Lithium SCHEMBL30194865 | 0.77 | HCAR2 (0.94) | HCAR2ALDH1A1KDM4EALOX15HSD17B10 | |
| Hydrochloric Acid SCHEMBL6741706 | 0.77 | HCAR2 (0.94) | HCAR2ALDH1A1KDM4EALOX15HSD17B10 | |
| SCHEMBL27550564 | 0.77 | HCAR2 (0.94) | HCAR2ALDH1A1KDM4EALOX15HSD17B10 | |
| Trimethylammonium SCHEMBL27659537 | 0.76 | HCAR2 (0.81) | HCAR2ALDH1A1KDM4EALOX15HSD17B10 | |
| Formaldehyde SCHEMBL28203822 | 0.75 | HCAR2 (0.90) | HCAR2ALDH1A1KDM4EALOX15HSD17B10 | |
| Urea SCHEMBL28229729 | 0.73 | HCAR2 (0.85) | HCAR2ALDH1A1KDM4EALOX15HSD17B10 | |
| Formaldehyde SCHEMBL28213410 | 0.73 | HCAR2 (0.85) | HCAR2ALDH1A1KDM4EALOX15HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040142920-A1 | Bipiperidinyl-derivatives and their use as chemokine receptors inhibitors | NOVARTIS | 2004-07-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040142920-A1 | Bipiperidinyl-derivatives and their use as chemokine receptors inhibitors | CCR5, CCR2, CXCR3 | HCAR2 190/4885ALDH1A1 1912/4885KDM4E 4814/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.