⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6725878 | 0.87 | IDH1 (0.32) | — | |
| SCHEMBL6727298 | 0.86 | P2RX3 (0.32) | — | |
| SCHEMBL3040310 | 0.78 | MAOA (0.42) | — | |
| SCHEMBL6726498 | 0.69 | P2RX7 (0.32) | — | |
| SCHEMBL3043311 | 0.69 | MAOA (0.32) | — | |
| SCHEMBL6727665 | 0.68 | DRD4 (0.34) | — | |
| SCHEMBL6238916 | 0.67 | MAOA (0.48) | — | |
| SCHEMBL6210178 | 0.58 | MAOA (0.43) | — | |
| SCHEMBL25276002 | 0.57 | MAOA (0.38) | — | |
| SCHEMBL6085956 | 0.56 | MAOA (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040147760-A1 | N-aryl-2-oxazolidinone-5-carboxamides and their derivatives | PHARMACIA & UPJOHN COMPANY | 2004-07-29 | — | — | US | claimed |