SCHEMBL673406

SCHEMBL673406

O=C(Cn1cncn1)c1ccc(F)cc1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.53
SMN1; SMN2 Q16637 1/20 0.53
CYP19A1 P11511 5/20 0.48
MAPT P10636 1/20 0.46
HTT P42858 1/20 0.46
KMT2A Q03164 1/20 0.46
NAMPT P43490 1/20 0.46
HDAC1 Q13547 1/20 0.46
HDAC6 Q9UBN7 1/20 0.46
PTPN1 P18031 1/20 0.44
NPC1 O15118 1/20 0.44
RAB9A P51151 1/20 0.44
HTR7 P34969 1/20 0.44
HSP90AA1 P07900 1/20 0.43
CYP3A4 P08684 1/20 0.43
CYP2C9 P11712 1/20 0.43
CYP11B1 P15538 1/20 0.43
CYP11B2 P19099 1/20 0.43
CYP2C19 P33261 1/20 0.43
ADRA1A P35348 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL412906 0.84 HDAC1 (0.49) CYP19A1MAPTHTTHDAC1HDAC6
SCHEMBL6558375 0.84 CYP1A2 (0.59) CYP19A1MAPTHTTKMT2AHDAC1
SCHEMBL7293623 0.84 HTT (0.63) LMNASMN1; SMN2CYP19A1MAPTHTT
SCHEMBL5066568 0.83 CYP19A1 (0.59) SMN1; SMN2CYP19A1MAPTKMT2AHDAC1
SCHEMBL9864864 0.83 PTPN1 (0.49) CYP19A1MAPTHTTHDAC1HDAC6
Hydrochloric Acid SCHEMBL409501 0.83 HTT (0.61) LMNASMN1; SMN2CYP19A1MAPTHTT
Hydrochloric Acid SCHEMBL412860 0.82 CYP19A1 (0.57) SMN1; SMN2CYP19A1MAPTKMT2AHSP90AA1
SCHEMBL13781424 0.81 HDAC1 (0.50) LMNASMN1; SMN2CYP19A1MAPTHTT
SCHEMBL407191 0.81 ALDH1A1 (0.55) LMNASMN1; SMN2CYP19A1MAPTKMT2A
SCHEMBL11021096 0.81 HTT (0.60) LMNASMN1; SMN2CYP19A1MAPTHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 80 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160249616-A1 METHOD OF INCREASING YIELD BY TREATING WITH FUNGICIDAL COMPOSITIONS ROTAM AGROCHEM INTERNATIONAL COMPANY LIMITED (HK) 2016-09-01 US claimed
US-20100325757-A1 FUNGICIDAL COMPOSITIONS AND THEIR APPLICATIONS IN AGRICULTURE MONSANTO TECHNOLOGY, LLC (US) 2010-12-23 US claimed
US-7836630-B2 Method of protecting seeds treated with a phytotoxic agent MONSANTO TECHNOLOGY LLC (US) 2010-11-23 US claimed
EP-2193711-A2 Fungicidal compositions and their applications in agriculture Monsanto Technology LLC (US) 2010-06-09 EP claimed
EP-1566996-B1 METHOD OF PROTECTING SEEDS TREATED WITH A PHYTOTOXIC AGENT MONSANTO TECHNOLOGY LLC (US) 2009-11-11 EP claimed
US-7098170-B2 Method of improving yield and vigor of plants by treatment with triazole and strobilurin-type fungicides MONSANTO TECHNOLOGY LLC (US) 2006-08-29 US claimed
WO-2004049778-A9 METHOD OF PROTECTING SEEDS TREATED WITH A PHYTOTOXIC AGENT MONSANTO TECHNOLOGY LLC (US) 2005-09-22 WO claimed
EP-1566996-A1 METHOD OF PROTECTING SEEDS TREATED WITH A PHYTOTOXIC AGENT Monsanto Technology LLC (US) 2005-08-31 EP claimed
EP-1429604-A4 FUNGICIDAL COMPOSITIONS AND THEIR APPLICATIONS IN AGRICULTURE MONSANTO TECHNOLOGY LLC (US) 2005-03-30 EP claimed
US-20040242540-A1 Fungicidal composition and their applications in agriculture ASRAR JAWED (US) 2004-12-02 US claimed
US-20040118040-A1 Method of protecting seeds treated with a phytotoxic agent MONSANTO TECHNOLOGY, L.L.C. 2004-06-24 US claimed
EP-1429604-A1 FUNGICIDAL COMPOSITIONS AND THEIR APPLICATIONS IN AGRICULTURE Monsanto Technology LLC (US) 2004-06-23 EP claimed
WO-2004049778-A1 METHOD OF PROTECTING SEEDS TREATED WITH A PHYTOTOXIC AGENT MONSANTO TECHNOLOGY, LLC (US) 2004-06-17 WO claimed
WO-2003026421-A1 FUNGICIDAL COMPOSITIONS AND THEIR APPLICATIONS IN AGRICULTURE MONSANTO TECHNOLOGY, LLC (US) 2003-04-03 WO claimed
US-20030060371-A1 Method of improving yield and vigor of plants by treatment with diazole, triazole and strobilurin-type fungicides MONSANTO TECHNOLOGY, L.L.C. (US) 2003-03-27 US claimed
EP-4697961-A2 AGROCHEMICAL FORMULATIONS FOR MITIGATING CRYSTALLIZATION Syngenta Crop Protection AG (CH) 2026-02-25 EP disclosed
US-20250008949-A1 MICRONIZED WAX AND SILICONE AGROCHEMICAL FORMULATION SYNGENTA CROP PROTECTION AG (CH) 2025-01-09 US disclosed
EP-0164246-A2 Triazole antifungal agents Pfizer Limited (GB) 1985-12-11 EP disclosed
EP-0122056-A1 Triazole antifungal agents Pfizer Limited (GB) 1984-10-17 EP disclosed
EP-0120609-A2 Fungicidal azolyl-ethyl-phosphonate derivatives IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1984-10-03 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100325757-A1 FUNGICIDAL COMPOSITIONS AND THEIR APPLICATIONS IN AGRICULTURE STS, FLNB, STOM LMNA 2766/4885SMN1; SMN2 2558/4885CYP19A1 656/4885
US-20040242540-A1 Fungicidal composition and their applications in agriculture STS, FLNB, SFXN3 LMNA 2835/4885SMN1; SMN2 2567/4885CYP19A1 601/4885
US-20030060371-A1 Method of improving yield and vigor of plants by treatment with diazole, triazole and strobilurin-type fungicides CYP4X1, SNX1, BROX LMNA 4406/4885SMN1; SMN2 633/4885CYP19A1 1506/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.