Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 2/20 | 0.49 |
| ▸ | GSK3B | P49841 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.44 |
| ▸ | CES2 | O00748 | 1/20 | 0.43 |
| ▸ | CES1 | P23141 | 1/20 | 0.43 |
| ▸ | MMP1 | P03956 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL673406 | 0.83 | LMNA (0.53) | PTPN1HDAC1HDAC6CYP19A1MAPT | |
| SCHEMBL9823573 | 0.83 | CYP19A1 (0.53) | HDAC1HDAC6CYP19A1MAPTHTT | |
| SCHEMBL7293623 | 0.80 | HTT (0.63) | GSK3BHDAC1HDAC6CYP19A1MAPT | |
| SCHEMBL6558375 | 0.80 | CYP1A2 (0.59) | HDAC1HDAC6CYP19A1MAPTHTT | |
| SCHEMBL412906 | 0.80 | HDAC1 (0.49) | GSK3BHDAC1HDAC6CYP19A1MAPT | |
| SCHEMBL10333391 | 0.80 | CYP1A2 (0.44) | HDAC1HDAC6CYP1A2CYP2C19 | |
| SCHEMBL11017333 | 0.80 | LMNA (0.46) | HDAC1HDAC6CYP19A1CYP1A2CYP2C9 | |
| SCHEMBL5066568 | 0.80 | CYP19A1 (0.59) | HDAC1HDAC6CYP19A1MAPTALDH1A1 | |
| Hydrochloric Acid SCHEMBL409501 | 0.79 | HTT (0.61) | HDAC1HDAC6CYP19A1MAPTHTT | |
| Hydrochloric Acid SCHEMBL412860 | 0.78 | CYP19A1 (0.57) | CYP19A1MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-3072468-A | — | — | None | — | — | JP | disclosed |
| JP-H0372468-A | TRIAZOLE COMPOUND AND ANTIFUNGAL AGENT CONTAINING THE SAME | SS PHARMACEUT CO LTD | 1991-03-27 | — | — | JP | disclosed |
| EP-0395899-A2 | Triazole compound, antimycotic preparation containing same, and method for the prevention and/or treatment of deep-seated mycosis by using same | SS PHARMACEUTICAL CO., LTD. (JP) | 1990-11-07 | — | — | EP | disclosed |
| EP-0235877-A1 | Triazolyl butanoic acid derivatives, process for their preparation and their use as plant growth regulators | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1987-09-09 | — | — | EP | disclosed |
| EP-0122693-B1 | ANTIFUNGAL DI(AZOLYL)PROPANOL DERIVATIVES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1987-07-08 | — | — | EP | disclosed |
| US-4625036-A | Antifungal azole compounds | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1986-11-25 | — | — | US | disclosed |
| EP-0122693-A1 | Antifungal di(azolyl)propanol derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1984-10-24 | — | — | EP | disclosed |