Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.35 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MAP2K7 | O14733 | 1/20 | 0.33 |
| ▸ | S100A4 | P26447 | 1/20 | 0.33 |
| ▸ | CDC25A | P30304 | 1/20 | 0.33 |
| ▸ | CDC25B | P30305 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 2/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6734186 | 0.79 | GABRA1 (0.46) | KEAP1NFE2L2MAPTGABRA1GABRB2 | |
| SCHEMBL8412113 | 0.75 | MAPT (0.38) | GAAMAPTNPSR1L3MBTL1MAP2K7 | |
| SCHEMBL8509614 | 0.75 | MAPT (0.38) | GAAMAPTNPSR1L3MBTL1MAP2K7 | |
| SCHEMBL5414986 | 0.74 | MAPT (0.35) | KEAP1NFE2L2GAAMAPTNPSR1 | |
| SCHEMBL8412567 | 0.74 | MAPT (0.37) | GAAMAPTNPSR1L3MBTL1MAP2K7 | |
| SCHEMBL8412562 | 0.74 | MAPT (0.37) | GAAMAPTNPSR1L3MBTL1MAP2K7 | |
| SCHEMBL6738181 | 0.70 | MAPT (0.40) | GAAMAPTNPSR1L3MBTL1 | |
| SCHEMBL8409658 | 0.70 | MAP2K7 (0.34) | GAAMAPTNPSR1L3MBTL1MAP2K7 | |
| SCHEMBL10570057 | 0.67 | PTGS2 (0.39) | KEAP1NFE2L2MAPTNPSR1L3MBTL1 | |
| SCHEMBL8854459 | 0.66 | GAA (0.32) | GAAMAPTNPSR1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6677277-B1 | Substituted sulphonyl amino(thio)carbonyl compounds and their use as herbicides | BAYER AKTIENGESELLSCHAFT (DE) | 2004-01-13 | — | — | US | disclosed |
| EP-0906293-B1 | SUBSTITUTED SULPHONYL AMINO(THIO)CARBONYL COMPOUNDS AND THEIR USE AS HERBICIDES | BAYER CROPSCIENCE AG (DE) | 2003-09-17 | — | — | EP | disclosed |
| EP-0906293-A1 | SUBSTITUTED SULPHONYL AMINO(THIO)CARBONYL COMPOUNDS AND THEIR USE AS HERBICIDES | BAYER AG (DE) | 1999-04-07 | — | — | EP | disclosed |
| WO-1997046540-A1 | SUBSTITUTED SULPHONYL AMINO(THIO)CARBONYL COMPOUNDS AND THEIR USE AS HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1997-12-11 | — | — | WO | disclosed |