Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.39 |
| ▸ | FEN1 | P39748 | 1/20 | 0.39 |
| ▸ | NSD2 | O96028 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | PARG | Q86W56 | 2/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6727322 | 0.79 | MAPT (0.35) | MAPTSMN1; SMN2LMNAKMT2AKDM4E | |
| SCHEMBL6737493 | 0.78 | NSD2 (0.44) | MAPTSMN1; SMN2LMNAKMT2AKDM4E | |
| SCHEMBL8509614 | 0.76 | MAPT (0.38) | MAPTLMNAKMT2AKDM4EMEN1 | |
| SCHEMBL8412113 | 0.76 | MAPT (0.38) | MAPTSMN1; SMN2HPGDGAAL3MBTL1 | |
| SCHEMBL8412562 | 0.75 | MAPT (0.37) | MAPTSMN1; SMN2LMNAKMT2AMEN1 | |
| SCHEMBL8412567 | 0.75 | MAPT (0.37) | MAPTLMNAKMT2AKDM4EMEN1 | |
| SCHEMBL15916202 | 0.73 | SLC40A1 (0.48) | MAPTSMN1; SMN2LMNAKMT2AKDM4E | |
| SCHEMBL10572395 | 0.73 | SMN1; SMN2 (0.47) | MAPTSMN1; SMN2LMNAKMT2AKDM4E | |
| SCHEMBL8409658 | 0.71 | MAP2K7 (0.34) | MAPTSMN1; SMN2LMNAKMT2AMEN1 | |
| SCHEMBL6734183 | 0.70 | KEAP1 (0.35) | MAPTGAAL3MBTL1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6677277-B1 | Substituted sulphonyl amino(thio)carbonyl compounds and their use as herbicides | BAYER AKTIENGESELLSCHAFT (DE) | 2004-01-13 | — | — | US | disclosed |
| EP-0906293-B1 | SUBSTITUTED SULPHONYL AMINO(THIO)CARBONYL COMPOUNDS AND THEIR USE AS HERBICIDES | BAYER CROPSCIENCE AG (DE) | 2003-09-17 | — | — | EP | disclosed |