Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 2/20 | 0.34 |
| ▸ | ACHE | P22303 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6741742 | 0.81 | PLAU (0.38) | ACHETSHRALDH1A1ALOX15HPGD | |
| SCHEMBL6740071 | 0.81 | CASP1 (0.36) | TSHRALDH1A1CYP3A4ALOX15HPGD | |
| SCHEMBL6740781 | 0.80 | MAPT (0.35) | TSHRALDH1A1CYP3A4ALOX15THRB | |
| SCHEMBL6271939 | 0.79 | KMT2A (0.47) | TSHRALDH1A1ALOX15GAAHTT | |
| SCHEMBL6735284 | 0.78 | BPTF (0.35) | TSHRALDH1A1CYP3A4ALOX15THRB | |
| SCHEMBL6742538 | 0.78 | GAA (0.41) | TSHRALDH1A1HPGDGAAHTT | |
| SCHEMBL6734298 | 0.78 | GAA (0.32) | ALDH1A1GAATDP1EGFR | |
| SCHEMBL6269473 | 0.77 | ALDH1A1 (0.43) | TSHRALDH1A1CYP3A4ALOX15THRB | |
| SCHEMBL6734215 | 0.76 | CYP3A4 (0.41) | TSHRALDH1A1CYP3A4ALOX15THRB | |
| SCHEMBL6270658 | 0.75 | MAOB (0.46) | ALDH1A1HPGDHSD17B10GAAEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6685751-B2 | SUCH AS 2-((2-AMINO-PHENYLAMINO)-METHYL)-1,4-DIAMINOBENZENE; HAIR DYES | WELLA AKTIENGESELLSCHAFT (DE) | 2004-02-03 | — | — | US | disclosed |
| US-6602302-B1 | Mixtures of carbocyclic amines such as 2-((2-aminophenylamino) -methyl)-1,4-diaminobenzene, couplers and developers, having photostability, wash and colorfastness, used for dyeing human hair | WELLA AG (DE) | 2003-08-05 | — | — | US | disclosed |
| US-20030110578-A1 | Substituted 1,4-diaminobenzene compounds and oxidation dye precursor compositions containing same | WELLA INTERNATIONAL OPERATIONS SWITZERLAND SARL (CH) | 2003-06-19 | — | — | US | disclosed |
| EP-1108708-B1 | 1,4-Diaminobenzene derivatives and colouring agents containing these compounds | WELLA AG (DE) | 2003-01-08 | — | — | EP | disclosed |
| EP-1108708-A1 | 1,4-Diaminobenzene derivatives and colouring agents containing these compounds | Wella Aktiengesellschaft (DE) | 2001-06-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030110578-A1 | Substituted 1,4-diaminobenzene compounds and oxidation dye precursor compositions containing same | KRT18, AOC1, DAO | BCHE 3234/4885ACHE 2422/4885TSHR 4650/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.