Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.31 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.31 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.31 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6734509 | 1.00 | ALDH1A1 (0.37) | ALDH1A1MAPTPOLBMEN1KMT2A | |
| SCHEMBL6732281 | 0.79 | GLO1 (0.41) | ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL6732284 | 0.79 | GLO1 (0.41) | ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL7617413 | 0.76 | MAPT (0.40) | ALDH1A1MAPTMEN1KMT2ACYP2C9 | |
| SCHEMBL6646404 | 0.76 | MAPT (0.40) | ALDH1A1MAPTMEN1KMT2ACYP2C9 | |
| SCHEMBL20043784 | 0.74 | MAPT (0.47) | ALDH1A1MAPTMEN1KMT2ACYP2C9 | |
| SCHEMBL11549074 | 0.69 | ALDH1A1 (0.46) | ALDH1A1MAPTPOLBMEN1KMT2A | |
| SCHEMBL2233968 | 0.69 | ALDH1A1 (0.46) | ALDH1A1MAPTPOLBMEN1KMT2A | |
| SCHEMBL11979152 | 0.67 | ALDH1A1 (0.43) | ALDH1A1MAPTPOLBMEN1KMT2A | |
| SCHEMBL3269694 | 0.67 | ALDH1A1 (0.43) | ALDH1A1MAPTPOLBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040220231-A1 | Substituted pyridines useful for inhibiting cholesteryl ester transfer protein activity | LEE LEN F (US) | 2004-11-04 | — | — | US | disclosed |
| US-6794396-B2 | Substituted pyridines useful for inhibiting cholesteryl ester transfer protein activity | PHARMACIA CORPORATION | 2004-09-21 | — | — | US | disclosed |
| US-20040038939-A1 | Substituted pyridines useful for inhibiting cholesteryl ester transfer protein activity | PHARMACIA CORPORATION | 2004-02-26 | — | — | US | disclosed |
| US-6605624-B1 | Preventing and/or treating atherosclerosis and other coronary artery diseases | PHARMACIA CORPORATION | 2003-08-12 | — | — | US | disclosed |
| EP-0181852-B1 | SUBSTITUTED 2,6-SUBSTITUTED PYRIDINE COMPOUNDS | Monsanto Company (US) | 1990-08-29 | — | — | EP | disclosed |
| US-4789395-A | POST- AND PRE-EMERGENT | MONSANTO COMPANY (US) | 1988-12-06 | — | — | US | disclosed |
| EP-0258201-A1 | 5-Sulfur substituted pyridine monocarboxylic herbicides | Monsanto Company (US) | 1988-03-02 | — | — | EP | disclosed |
| US-4655816-A | PLANT GROWTH REGULATORS | MONSANTO COMPANY (US) | 1987-04-07 | — | — | US | disclosed |
| EP-0181852-A1 | Substituted 2,6-substituted pyridine compounds | Monsanto Company (US) | 1986-05-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040038939-A1 | Substituted pyridines useful for inhibiting cholesteryl ester transfer protein activity | CETP, CES1, MTTP | ALDH1A1 1154/4885MAPT 3616/4885POLB 4641/4885 |
| US-20040220231-A1 | Substituted pyridines useful for inhibiting cholesteryl ester transfer protein activity | CETP, MTTP, LCAT | ALDH1A1 1364/4885MAPT 3344/4885POLB 4631/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.