SCHEMBL6734700

SCHEMBL6734700

O=c1n(-c2cc(O)c([N+](=O)[O-])cc2F)nc2ccc(Cl)cn12

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALKBH5 Q6P6C2 2/20 0.35
FTO Q9C0B1 1/20 0.35
MAPT P10636 7/20 0.34
MAPK1 P28482 5/20 0.34
MEN1 O00255 3/20 0.34
KMT2A Q03164 3/20 0.34
GAA P10253 2/20 0.34
LMNA P02545 3/20 0.33
ALDH1A1 P00352 3/20 0.33
POLB P06746 2/20 0.33
L3MBTL1 Q9Y468 2/20 0.33
PKM P14618 2/20 0.33
KDM4E B2RXH2 1/20 0.33
THRB P10828 1/20 0.33
IDO1 P14902 1/20 0.33
RECQL P46063 1/20 0.33
TDO2 P48775 1/20 0.33
BLM P54132 1/20 0.33
CASP6 P55212 1/20 0.33
TDP1 Q9NUW8 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6724660 0.90 ALDH1A1 (0.35) MAPTMAPK1GAALMNAALDH1A1
SCHEMBL6727422 0.88 ALDH1A1 (0.35) ALKBH5MAPTMAPK1GAALMNA
SCHEMBL6727669 0.87 MAPK1 (0.38) ALKBH5MAPTMAPK1GAALMNA
SCHEMBL6725089 0.84 TDP1 (0.37) MAPTMEN1KMT2ALMNAALDH1A1
SCHEMBL7014884 0.79 GPR139 (0.34) MEN1KMT2AGAALMNAALDH1A1
SCHEMBL7014817 0.76 DHODH (0.36) MAPTALDH1A1SMN1; SMN2
SCHEMBL6730676 0.74 ALDH1A1 (0.36) ALDH1A1L3MBTL1KDM4ESMN1; SMN2
SCHEMBL6729658 0.70 ALDH1A1 (0.38) MAPTMAPK1LMNAALDH1A1POLB
SCHEMBL6729888 0.69 ACLY (0.32) MEN1KMT2AALDH1A1
SCHEMBL6730520 0.68 S1PR3 (0.36) MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040063580-A1 Bicyclic triazolone derivatives and a herbicides containing the same SUMITOMO CHEMICAL TAKEDA AGRO COMPANY, LIMITED (JP) 2004-04-01 US disclosed
EP-1333031-A1 BICYCLIC TRIAZOLONE DERIVATIVES AND HERBICIDES CONTAINING THE SAME Sumitomo Chemical Takeda Agro Company, Limited (JP) 2003-08-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040063580-A1 Bicyclic triazolone derivatives and a herbicides containing the same WEE1, WEE2, BAK1 ALKBH5 891/4885FTO 2823/4885MAPT 4198/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.