Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 known ✓ | P08172 | 1/20 | 0.30 |
| ▸ | CHRM1 known ✓ | P11229 | 1/20 | 0.30 |
| ▸ | CHRM3 known ✓ | P20309 | 1/20 | 0.30 |
| ▸ | SLC6A2 known ✓ | P23975 | 1/20 | 0.30 |
| ▸ | SLC6A3 known ✓ | Q01959 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 3/20 | 0.32 |
| ▸ | GPR3 | P46089 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.30 |
| ▸ | CCL2 | P13500 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.30 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.30 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methane SCHEMBL6558661 | 0.98 | CYP2D6 (0.34) | CYP2D6HTR6HTR2A | |
| Ethane SCHEMBL8540098 | 0.97 | CYP2D6 (0.33) | CYP2D6HTR6HTR2AGPR3BRD4 | |
| Hydrochloric Acid SCHEMBL7272244 | 0.88 | ELANE (0.36) | KDM4ELMNAHSD17B10 | |
| Hydrochloric Acid SCHEMBL137960 | 0.85 | HTR2A (0.39) | CYP2D6HTR6HTR2ABRD4CCL2 | |
| Hydrochloric Acid SCHEMBL29424565 | 0.85 | HTR2A (0.39) | CYP2D6HTR6HTR2ABRD4CCL2 | |
| Hydrochloric Acid SCHEMBL7269966 | 0.84 | ELANE (0.34) | KDM4ELMNAHSD17B10 | |
| Hydrochloric Acid SCHEMBL7271193 | 0.84 | HTR7 (0.30) | HTR2B | |
| Hydrochloric Acid SCHEMBL2479388 | 0.83 | CYP1A2 (0.38) | SLC6A2SLC6A3 | |
| Hydrochloric Acid SCHEMBL820052 | 0.83 | HTR2A (0.38) | CYP2D6HTR6HTR2ABRD4CCL2 | |
| Hydrochloric Acid SCHEMBL30533388 | 0.83 | HTR2A (0.38) | CYP2D6HTR6HTR2ABRD4CCL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11634513-B2 | Process for preparing catalysts and catalyst compositions | FORMOSA PLASTICS CORPORATION, U.S.A. (US) | 2023-04-25 | — | — | US | claimed |
| US-20220242976-A1 | PROCESS FOR PREPARING CATALYSTS AND CATALYST COMPOSITIONS | FORMOSA PLASTICS CORPORATION, U.S.A. (US) | 2022-08-04 | — | — | US | claimed |
| US-6410665-B1 | POLYMERIZATION COORDINATION CATALYST FOR ALPHA-OLEFIN | BASELL POLYOLEFINE GMBH (DE) | 2002-06-25 | — | — | US | claimed |
| US-6124231-A | Supported catalyst system, processes for its preparation, and its use for the polymerization of olefins | TARGOR GMBH (DE) | 2000-09-26 | — | — | US | claimed |
| EP-0528287-B1 | Bridged chiral metallocenes, process for their preparation and their use as catalysts | TARGOR GMBH (DE) | 1998-11-11 | — | — | EP | claimed |
| EP-4536395-A1 | CLAY COMPOSITE SUPPORT-ACTIVATORS AND CATALYST COMPOSITIONS | Formosa Plastics Corporation, U.S.A. (US) | 2025-04-16 | — | — | EP | disclosed |
| US-12152101-B2 | Process for preparing catalysts and catalyst compositions | FORMOSA PLASTICS CORPORATION, U.S.A. (US) | 2024-11-26 | — | — | US | disclosed |
| US-20240084051-A1 | PROCESS FOR PREPARING CATALYSTS AND CATALYST COMPOSITIONS | FORMOSA PLASTICS CORPORATION, U.S.A. (US) | 2024-03-14 | — | — | US | disclosed |
| US-20230399420-A1 | CLAY COMPOSITE SUPPORT-ACTIVATORS AND CATALYST COMPOSITIONS | FORMOSA PLASTICS CORPORATION, U.S.A. (US) | 2023-12-14 | — | — | US | disclosed |
| WO-2023239560-A1 | CLAY COMPOSITE SUPPORT-ACTIVATORS AND CATALYST COMPOSITIONS | FORMOSA PLASTICS CORPORATON, U.S.A. (US) | 2023-12-14 | — | — | WO | disclosed |
| US-11814461-B2 | Process for preparing catalysts and catalyst compositions | FORMOSA PLASTICS CORPORATION, U.S.A. (US) | 2023-11-14 | — | — | US | disclosed |
| US-20230242683-A1 | PROCESS FOR PREPARING CATALYSTS AND CATALYST COMPOSITIONS | FORMOSA PLASTICS CORPORATION, U.S.A. (US) | 2023-08-03 | — | — | US | disclosed |
| US-6329313-B1 | CHEMICAL COMPOUNDS WITH SUPPORTS | BASELL POLYOLEFINE GMBH (DE) | 2001-12-11 | — | — | US | disclosed |
| US-6124231-A | Supported catalyst system, processes for its preparation, and its use for the polymerization of olefins | TARGOR GMBH (DE) | 2000-09-26 | — | — | US | disclosed |
| EP-0942006-A2 | Catalyst for olefin polymer production and process for olefin polymer production employing the catalyst | TOSOH CORPORATION (JP) | 1999-09-15 | — | — | EP | disclosed |
| EP-0927201-A1 | CATALYST SYSTEM FOR (CO)POLYMERIZATION OF OLEFINS AND PROCESS FOR THE PREPARATION OF OLEFIN (CO)POLYMERS USING THE CATALYST SYSTEM | Hyundai Petrochemical Co., Ltd. (KR) | 1999-07-07 | — | — | EP | disclosed |
| US-5770752-A | Process for reducing the concentration of by-products in product mixtures | TARGOR GMBH (DE) | 1998-06-23 | — | — | US | disclosed |
| WO-1998009996-A1 | CATALYST SYSTEM FOR (CO)POLYMERIZATION OF OLEFINS AND PROCESS FOR THE PREPARATION OF OLEFIN (CO)POLYMERS USING THE CATALYST SYSTEM | HYUNDAI PETROCHEMICAL CO., LTD. (KR) | 1998-03-12 | — | — | WO | disclosed |
| US-5646083-A | Process for the preparation of a bridged metallocene compound as well as a catalyst component and a process for the polymerization of olefins | DSM N.V. (NL) | 1997-07-08 | — | — | US | disclosed |
| US-5391789-A | Bridged, chiral metallocenes, processes for their preparation and their use as catalysts | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-02-21 | — | — | US | disclosed |