Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALPL | P05186 | 1/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | CNR1 | P21554 | 5/20 | 0.43 |
| ▸ | CDC7 | O00311 | 1/20 | 0.42 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6741266 | 0.87 | ALPL (0.47) | ALPLSLC6A3CNR1CDC7DBF4 | |
| SCHEMBL6740040 | 0.83 | ALPL (0.44) | ALPLCNR1CDC7DBF4KDM4E | |
| SCHEMBL6987268 | 0.79 | ALPL (0.41) | ALPLSLC6A3CNR1MAPTKDM4E | |
| SCHEMBL4371693 | 0.78 | ALPL (0.49) | ALPLSLC6A3CNR1CDC7DBF4 | |
| SCHEMBL6985020 | 0.77 | CNR1 (0.40) | ALPLCNR1CDC7DBF4MAPT | |
| SCHEMBL4368811 | 0.76 | CDC7 (0.51) | ALPLSLC6A3CNR1CDC7DBF4 | |
| SCHEMBL6741291 | 0.74 | MAPT (0.37) | ALPLMAPTKDM4EALDH1A1HPGD | |
| SCHEMBL6734941 | 0.74 | ALPL (0.56) | ALPLSLC6A3CNR1MAPTKDM4E | |
| SCHEMBL3436162 | 0.74 | MAPT (0.57) | CNR1CDC7DBF4MAPTKDM4E | |
| SCHEMBL14953190 | 0.72 | CDC7 (0.43) | ALPLCNR1CDC7DBF4KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040023807-A1 | 3-Arylisothiazoles and their use as herbicides | BASF AKTIENGESELLSCHAFT (DE) | 2004-02-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040023807-A1 | 3-Arylisothiazoles and their use as herbicides | DDT, HAX1, SULT1E1 | ALPL 3150/4885SLC6A3 398/4885CNR1 1046/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.