Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALPL | P05186 | 9/20 | 0.56 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.44 |
| ▸ | ABL1 | P00519 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14953117 | 0.85 | ALPL (0.52) | ALPLKDM4E | |
| SCHEMBL3435530 | 0.85 | MAPT (0.54) | ALPLMAPTPOLBKDM4E | |
| SCHEMBL11001807 | 0.81 | MAPT (0.54) | ALPLSLC6A3MAPTKDM4E | |
| SCHEMBL3435435 | 0.81 | ALPL (0.58) | ALPLMAPTKDM4E | |
| SCHEMBL11000948 | 0.78 | SLC6A3 (0.48) | SLC6A3MAPTPOLBABL1 | |
| SCHEMBL10049034 | 0.77 | ALDH1A1 (0.50) | ALPLPOLBKDM4E | |
| SCHEMBL14800013 | 0.75 | HSP90AA1 (0.43) | ALPLMAPTPOLBKDM4E | |
| SCHEMBL6735476 | 0.74 | ALPL (0.49) | ALPLSLC6A3MAPTPOLBKDM4E | |
| SCHEMBL6741788 | 0.74 | ALPL (0.38) | ALPLMAPTPOLBMRGPRX4KDM4E | |
| SCHEMBL24984506 | 0.73 | ALPL (0.58) | ALPLSLC6A3MAPTPOLBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040023807-A1 | 3-Arylisothiazoles and their use as herbicides | BASF AKTIENGESELLSCHAFT (DE) | 2004-02-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040023807-A1 | 3-Arylisothiazoles and their use as herbicides | DDT, HAX1, SULT1E1 | ALPL 3150/4885SLC6A3 398/4885MAPT 2566/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.