Methacrylic Acid

Methacrylic Acid

SCHEMBL673567

C=C(C)C(=O)O.C[N+](C)(C)CCCO.[Cl-]

nearest known ligand 0.62

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA

The experimentally established mechanism targets of Methacrylic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE known ✓ P22303 2/20 0.45
CHRM1 known ✓ P11229 2/20 0.38
CHRM3 known ✓ P20309 2/20 0.38
CHRM2 known ✓ P08172 1/20 0.34
CYP3A4 P08684 1/20 0.42
SLC5A7 Q9GZV3 1/20 0.42
APEX1 P27695 3/20 0.39
NPSR1 Q6W5P4 1/20 0.39
BBOX1 O75936 2/20 0.38
CHRM5 P08912 2/20 0.38
POLB P06746 1/20 0.38
BLM P54132 1/20 0.38
ATM Q13315 1/20 0.38
MEN1 O00255 3/20 0.37
KMT2A Q03164 3/20 0.37
LMNA P02545 3/20 0.37
NFKB1 P19838 2/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
KDM4E B2RXH2 1/20 0.35
HSD17B10 Q99714 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methacrylic Acid SCHEMBL8074057 0.98 ACHE (0.46) ACHECYP3A4SLC5A7APEX1NPSR1
Methacrylic Acid SCHEMBL2231531 0.96 ACHE (0.45) ACHECYP3A4SLC5A7APEX1NPSR1
Choline SCHEMBL28876404 0.87 CYP3A4 (0.59) ACHECYP3A4SLC5A7APEX1CHRM5
Acetic Acid SCHEMBL27956805 0.87 ACHE (0.52) ACHECYP3A4SLC5A7APEX1NPSR1
Oxalic Acid SCHEMBL28324568 0.87 CYP3A4 (0.50) ACHECYP3A4SLC5A7APEX1NPSR1
Hydrochloric Acid SCHEMBL10949777 0.86 TDP1 (0.48) ACHECYP3A4SLC5A7APEX1NPSR1
Methacrylic Acid SCHEMBL2231529 0.86 ACHE (0.43) ACHECYP3A4SLC5A7APEX1NPSR1
Choline SCHEMBL29111296 0.85 LMNA (0.55) ACHECYP3A4SLC5A7APEX1CHRM5
Choline SCHEMBL29809930 0.85 LMNA (0.55) ACHECYP3A4SLC5A7APEX1CHRM5
Methacrylic Acid SCHEMBL8621490 0.83 ACHE (0.45) ACHECYP3A4SLC5A7APEX1NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5935844-A Porous cellulose carrier for immobilizing microorganisms to convert nitrogen compounds BIOMATERIAL CO., LTD. (JP) 1999-08-10 US claimed
EP-0758680-A2 Carrier for immobilizing microorganisms, and method for converting nitrogen compounds in a liquid using the same Matsumura, Masatoshi (JP) 1997-02-19 EP claimed
US-11566095-B2 Graft copolymer and soil resistant composition DAIKIN INDUSTRIES. LTD. (JP) 2023-01-31 US disclosed
US-20210130522-A1 GRAFT COPOLYMER AND SOIL RESISTANT COMPOSITION DAIKIN INDUSTRIES, LTD. (JP) 2021-05-06 US disclosed
US-20130017744-A1 GRAFT COPOLYMER AND REPELLENT COMPOSITION DAIKIN INDUSTRIES, LTD. (JP) 2013-01-17 US disclosed
EP-1967534-B1 ADHESIVE COMPOSITION KURARAY CO (JP) 2011-08-24 EP disclosed
US-7968662-B2 Repellent composition containing graft copolymer, graft copolymer and method of preparing graft copolymer DAIKIN INDUSTRIES, LTD. (JP) 2011-06-28 US disclosed
EP-1917282-B8 REPELLENT COMPOSITION CONTAINING GRAFT COPOLYMER, GRAFT COPOLYMER AND METHOD OF PREPARING GRAFT COPOLYMER DAIKIN IND LTD (JP) 2011-01-12 EP disclosed
EP-1917282-B1 REPELLENT COMPOSITION CONTAINING GRAFT COPOLYMER, GRAFT COPOLYMER AND METHOD OF PREPARING GRAFT COPOLYMER DAIKIN IND LTD (JP) 2010-11-03 EP disclosed
US-7728061-B2 Adhesive composition KURARAY CO., LTD. (JP) 2010-06-01 US disclosed
US-7622194-B2 use of a transparent support having specific physical properties during the spreading of a functional layer makes it possible to control the spread and the penetration of solvent and hence provide a good quality optical film having little coating defects, reducing impact of residual solvent; LCDs FUJIFILM CORPORATION (JP) 2009-11-24 US disclosed
EP-1251150-A1 GRAFT COPOLYMER AND SOLUTION TYPE WATER-AND-OIL REPELLANT COMPOSITION CONTAINING THE SAME Daikin Industries, Ltd. (JP) 2002-10-23 EP disclosed
EP-1243605-A1 GRAFT POLYMER, PROCESS FOR THE PRODUCTION THEREOF AND SOLUTION-TYPE WATER- AND OIL-REPELLENT COMPOSITIONS CONTAINING THE POLYMER Daikin Industries, Ltd. (JP) 2002-09-25 EP disclosed
EP-0682146-B1 TEXTILE PRODUCT TREATMENT DAIKIN IND LTD (JP) 2001-11-21 EP disclosed
US-6210858-B1 HIGH AND LOW REFRACTIVE INDEX LAYERS, INORGANIC FINE PARTICLES HAVING A MEAN PARTICLE SIZE OF 1-200 NM AND A CROSSLINKED ANIONIC POLYMER COMPRISING A PHOSPHORIC ACID GROUP OR A SULFONIC ACID GROUP AS AN ANIONIC GROUP IN AN AMOUNT OF FUJI PHOTO FILM CO., LTD. (JP) 2001-04-03 US disclosed
US-5935844-A Porous cellulose carrier for immobilizing microorganisms to convert nitrogen compounds BIOMATERIAL CO., LTD. (JP) 1999-08-10 US disclosed
US-5614099-A POLYAMIDE SKIN LAYER COATED WITH CROSSLINKED POLYETHYLENIMINE, ANIONIC AND CATIONIC POLYMERS, MULTISTAGE DESALINATION NITTO DENKO CORPORATION (JP) 1997-03-25 US disclosed
US-5614123-A GRAFT FLUOROCOPOLYMER DAIKIN INDUSTRIES LTD. (JP) 1997-03-25 US disclosed
EP-0758680-A2 Carrier for immobilizing microorganisms, and method for converting nitrogen compounds in a liquid using the same Matsumura, Masatoshi (JP) 1997-02-19 EP disclosed
EP-0682146-A1 TEXTILE PRODUCT TREATMENT DAIKIN INDUSTRIES, LIMITED (JP) 1995-11-15 EP disclosed