Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4387763 | 0.92 | CCR5 (0.80) | CCR5KCNH2 | |
| SCHEMBL3841540 | 0.87 | CCR5 (1.00) | CCR5KCNH2 | |
| SCHEMBL3839041 | 0.86 | CCR5 (0.66) | CCR5KCNH2 | |
| SCHEMBL3837714 | 0.85 | CCR5 (1.00) | CCR5KCNH2 | |
| SCHEMBL4391719 | 0.83 | CCR5 (0.50) | CCR5KCNH2 | |
| SCHEMBL12207173 | 0.83 | CCR5 (0.87) | CCR5KCNH2 | |
| SCHEMBL14024815 | 0.81 | CCR5 (0.84) | CCR5KCNH2 | |
| SCHEMBL4394644 | 0.81 | CCR5 (0.88) | CCR5KCNH2 | |
| SCHEMBL3837942 | 0.79 | CCR5 (1.00) | CCR5KCNH2 | |
| SCHEMBL4384733 | 0.78 | CCR5 (0.82) | CCR5KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040142920-A1 | Bipiperidinyl-derivatives and their use as chemokine receptors inhibitors | NOVARTIS | 2004-07-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040142920-A1 | Bipiperidinyl-derivatives and their use as chemokine receptors inhibitors | CCR5, CCR2, CXCR3 | CCR5 1/4885KCNH2 4158/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.