Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNQ3 | O43525 | 3/20 | 0.67 |
| ▸ | KCNQ2 | O43526 | 3/20 | 0.67 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.50 |
| ▸ | KCNQ4 | P56696 | 1/20 | 0.48 |
| ▸ | KCNQ5 | Q9NR82 | 1/20 | 0.48 |
| ▸ | ACACB | O00763 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | ACACA | Q13085 | 1/20 | 0.44 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.43 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6736357 | 1.00 | KCNQ3 (0.67) | KCNQ3KCNQ2SCN9AKCNQ4KCNQ5 | |
| SCHEMBL6732699 | 0.89 | KCNQ3 (0.71) | KCNQ3KCNQ2SCN9AKCNQ4KCNQ5 | |
| SCHEMBL6732078 | 0.89 | KCNQ3 (0.71) | KCNQ3KCNQ2SCN9AKCNQ4KCNQ5 | |
| SCHEMBL6737872 | 0.82 | RAB9A (0.54) | RAB9ALMNAFFAR1 | |
| SCHEMBL6737874 | 0.82 | RAB9A (0.54) | RAB9ALMNAFFAR1 | |
| SCHEMBL6740611 | 0.79 | KCNQ3 (0.61) | KCNQ3KCNQ2SCN9AKCNQ4KCNQ5 | |
| SCHEMBL6740608 | 0.79 | KCNQ3 (0.61) | KCNQ3KCNQ2SCN9AKCNQ4KCNQ5 | |
| SCHEMBL6732121 | 0.78 | KCNQ3 (0.78) | KCNQ3KCNQ2SCN9AKCNQ4KCNQ5 | |
| SCHEMBL6741277 | 0.78 | KCNQ3 (0.85) | KCNQ3KCNQ2SCN9AKCNQ4KCNQ5 | |
| SCHEMBL6741274 | 0.78 | KCNQ3 (0.85) | KCNQ3KCNQ2SCN9AKCNQ4KCNQ5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040235830-A1 | Substituted cyclohexane derivatives and the use thereof in medicaments for treating cardiovascular diseases | BAYER AKTIENGESELLSCHAFT (DE) | 2004-11-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040235830-A1 | Substituted cyclohexane derivatives and the use thereof in medicaments for treating cardiovascular diseases | CYP46A1, REN, CYP11B2 | KCNQ3 3634/4885KCNQ2 3637/4885SCN9A 4715/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.