Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCA | P17252 | 5/20 | 0.81 |
| ▸ | PRKD3 | O94806 | 4/20 | 0.81 |
| ▸ | PRKCG | P05129 | 4/20 | 0.81 |
| ▸ | PRKCB | P05771 | 4/20 | 0.81 |
| ▸ | PRKCH | P24723 | 4/20 | 0.81 |
| ▸ | PRKCI | P41743 | 4/20 | 0.81 |
| ▸ | PRKCE | Q02156 | 4/20 | 0.81 |
| ▸ | PRKCQ | Q04759 | 4/20 | 0.81 |
| ▸ | PRKCZ | Q05513 | 4/20 | 0.81 |
| ▸ | PRKCD | Q05655 | 4/20 | 0.81 |
| ▸ | PRKD1 | Q15139 | 4/20 | 0.81 |
| ▸ | USP2 | O75604 | 2/20 | 0.81 |
| ▸ | TP53 | P04637 | 2/20 | 0.81 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.81 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.81 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.81 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.81 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.81 |
| ▸ | TSHR | P16473 | 1/20 | 0.81 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.81 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phorbol Myristate Acetate SCHEMBL19271683 | 0.89 | PRKCA (1.00) | PRKCAPRKD3PRKCGPRKCBPRKCH | |
| Phorbol Myristate Acetate SCHEMBL17368149 | 0.89 | PRKCA (1.00) | PRKCAPRKD3PRKCGPRKCBPRKCH | |
| SCHEMBL16174732 | 0.89 | PRKCA (1.00) | PRKCAPRKD3PRKCGPRKCBPRKCH | |
| Phorbol Myristate Acetate SCHEMBL22722418 | 0.89 | PRKCA (1.00) | PRKCAPRKD3PRKCGPRKCBPRKCH | |
| Phorbol Myristate Acetate SCHEMBL21165759 | 0.89 | PRKCA (1.00) | PRKCAPRKD3PRKCGPRKCBPRKCH | |
| Phorbol Myristate Acetate SCHEMBL22736719 | 0.89 | PRKCA (1.00) | PRKCAPRKD3PRKCGPRKCBPRKCH | |
| Phorbol Myristate Acetate SCHEMBL18550994 | 0.89 | PRKCA (1.00) | PRKCAPRKD3PRKCGPRKCBPRKCH | |
| Phorbol Myristate Acetate SCHEMBL15423125 | 0.89 | PRKCA (1.00) | PRKCAPRKD3PRKCGPRKCBPRKCH | |
| SCHEMBL3707129 | 0.89 | PRKCA (1.00) | PRKCAPRKD3PRKCGPRKCBPRKCH | |
| Phorbol Myristate Acetate SCHEMBL115567 | 0.89 | PRKCA (1.00) | PRKCAPRKD3PRKCGPRKCBPRKCH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040253608-A1 | Compounds with anti-KS and anti-HIV activity | ALTACHEM PHARMA LTD. (CA) | 2004-12-16 | — | — | US | disclosed |
| US-6683050-B1 | LACKING HUMAN CHORIONIC GONADOTROPIN STEROIDOGENIC AND LUTROPIN CHORIOGONADOTROPIN RECEPTOR BINDING ABILITIES; KAPOSI'S SARCOMA (KS) | ALTACHEM PHARMA LTD. (CA) | 2004-01-27 | — | — | US | disclosed |
| EP-1017722-A2 | COMPOUNDS WITH ANTI-KS AND ANTI-HIV ACTIVITY | Altachem Pharma Ltd. (CA) | 2000-07-12 | — | — | EP | disclosed |
| US-5886019-A | REPLACEMENT OF HYDROXYMETHYL OR-ETHYL GROUP ON TRICYCLIC AROMATIC HETEROCYCLIC COMPOUNDS HAVING INDOLE, INDENE, BENZOFURAN OR BENZOTHIOPHENE SKELETON; ANTIINFLAMMATORY, ANTIVIRAL | PROCYON PHARMACEUTICALS, INC. (US) | 1999-03-23 | — | — | US | disclosed |
| WO-1999006438-A2 | COMPOUNDS WITH ANTI-KS AND ANTI-HIV ACTIVITY | UNIVERSITE DE MONTREAL (CA) | 1999-02-11 | — | — | WO | disclosed |