Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHKA | P35790 | 2/20 | 0.50 |
| ▸ | LTA4H | P09960 | 1/20 | 0.45 |
| ▸ | DYRK1A | Q13627 | 4/20 | 0.45 |
| ▸ | CLK2 | P49760 | 1/20 | 0.45 |
| ▸ | CLK3 | P49761 | 1/20 | 0.45 |
| ▸ | PAICS | P22234 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | GSK3B | P49841 | 4/20 | 0.41 |
| ▸ | MET | P08581 | 2/20 | 0.41 |
| ▸ | ABL1 | P00519 | 1/20 | 0.41 |
| ▸ | SRC | P12931 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
| ▸ | MTOR | P42345 | 1/20 | 0.40 |
| ▸ | WNT1 | P04628 | 1/20 | 0.39 |
| ▸ | GNRHR | P30968 | 1/20 | 0.38 |
| ▸ | METAP2 | P50579 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6743075 | 0.91 | HRH3 (0.40) | CHKALTA4HDYRK1ACLK2CLK3 | |
| SCHEMBL7254329 | 0.87 | HRH3 (0.43) | CHKADYRK1AGSK3BMETHRH1 | |
| SCHEMBL6742704 | 0.84 | LTA4H (0.47) | LTA4HDYRK1AGSK3BMETWNT1 | |
| SCHEMBL6743939 | 0.80 | CHKA (0.51) | CHKAKDM4EABL1SRCGNRHR | |
| SCHEMBL28318435 | 0.79 | LTA4H (0.52) | CHKALTA4HDYRK1ACLK2CLK3 | |
| SCHEMBL6738636 | 0.78 | CHKA (0.58) | CHKAGSK3BMETABL1SRC | |
| SCHEMBL24247917 | 0.77 | LTA4H (0.47) | CHKALTA4HDYRK1ACLK2CLK3 | |
| SCHEMBL7254567 | 0.72 | TLR9 (0.48) | DYRK1AKDM4EGSK3B | |
| SCHEMBL1331611 | 0.72 | FAAH (0.58) | CHKAKDM4E | |
| SCHEMBL13041008 | 0.72 | FAAH (0.58) | CHKAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6689772-B1 | ANTINEOPLASTIC AGENTS; OSTEOPOROSIS; POLYCYSTIC KIDNEY DISEASE; ANTIVIRAL AGENTS | WYETH | 2004-02-10 | — | — | US | disclosed |