Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDPK1 | O15530 | 1/20 | 0.47 |
| ▸ | ACP3 | P15309 | 1/20 | 0.47 |
| ▸ | TACR1 | P25103 | 4/20 | 0.45 |
| ▸ | MMP8 | P22894 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | LDHA | P00338 | 1/20 | 0.42 |
| ▸ | LDHB | P07195 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 3/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CACNA1A | O00555 | 1/20 | 0.41 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.41 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.41 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.41 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6880963 | 0.81 | PDPK1 (0.60) | PDPK1ACP3TACR1CNR2LDHA | |
| SCHEMBL9511451 | 0.79 | SMN1; SMN2 (0.43) | ACP3TACR1SLC6A9POLB | |
| SCHEMBL5348695 | 0.79 | NPSR1 (0.47) | NPSR1POLBPPARGFFAR1EPHX2 | |
| SCHEMBL28147664 | 0.79 | NPSR1 (0.49) | NPSR1POLBPPARGFFAR1EPHX2 | |
| SCHEMBL1043699 | 0.79 | NPSR1 (0.49) | MMP8NPSR1POLBPPARGFFAR1 | |
| SCHEMBL10869302 | 0.79 | MMP8 (0.51) | MMP8TSHR | |
| SCHEMBL7090567 | 0.78 | MMP8 (0.52) | PDPK1ACP3TACR1MMP8NPSR1 | |
| SCHEMBL27103619 | 0.78 | SLC6A9 (0.52) | SLC6A9PPARGTSHRCACNA1C | |
| SCHEMBL6809652 | 0.78 | MMP8 (0.48) | MMP8NPSR1POLBPPARGFFAR1 | |
| SCHEMBL6675458 | 0.77 | CES2 (0.56) | NPSR1POLBPPARGFFAR1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1042372-B1 | COMPONENTS AND CATALYSTS FOR THE POLYMERIZATION OF OLEFINS | BASELL POLIOLEFINE SPA (IT) | 2004-07-14 | — | — | EP | claimed |
| US-6605562-B1 | Comprising TiCl4, MgCl2 and an electron donor compound selected from heteroatom containing esters of malonic acids; heteroatoms are preferably selected from F, Cl, Br, and Si | BASELL POLIOLEFINE ITALIA S.P.A. (IT) | 2003-08-12 | — | — | US | claimed |
| EP-1042372-B1 | COMPONENTS AND CATALYSTS FOR THE POLYMERIZATION OF OLEFINS | BASELL POLIOLEFINE SPA (IT) | 2004-07-14 | — | — | EP | disclosed |
| US-6699814-B2 | CATALYST COMPRISING PRODUCT OF REACTION BETWEEN SOLID CATALYST COMPONENT COMPRISING MAGNESIUM, TITANIUM, HALOGEN AND HETEROATOM CONTAINING MALONATE, ALKYLALUMINUM COMPOUND AND, OPTIONALLY, ONE OR MORE ELECTRON-DONOR COMPOUNDS | BASELL POLIOLEFINE ITALIA S.P.A. (IT) | 2004-03-02 | — | — | US | disclosed |
| US-6689850-B2 | Process for the polymerization of olefins | BASELL POLIOLEFINE ITALIA S.P.A. (IT) | 2004-02-10 | — | — | US | disclosed |
| US-20030207754-A1 | Process for the polymerization of olefins | MORINI GIAMPIERO (IT) | 2003-11-06 | — | — | US | disclosed |
| US-20030207755-A1 | Heteroatom containing malonates used in catalysts for the polymerization of olefins | MORINI GIAMPIERO (IT) | 2003-11-06 | — | — | US | disclosed |
| US-20030199388-A1 | Catalysts for the polymerization of olefins | EQUISTAR CHEMICALS, LP | 2003-10-23 | — | — | US | disclosed |
| US-6605562-B1 | Comprising TiCl4, MgCl2 and an electron donor compound selected from heteroatom containing esters of malonic acids; heteroatoms are preferably selected from F, Cl, Br, and Si | BASELL POLIOLEFINE ITALIA S.P.A. (IT) | 2003-08-12 | — | — | US | disclosed |
| EP-1042372-A1 | COMPONENTS AND CATALYSTS FOR THE POLYMERIZATION OF OLEFINS | Montell Technology Company bv (NL) | 2000-10-11 | — | — | EP | disclosed |
| WO-2000026259-A1 | COMPONENTS AND CATALYSTS FOR THE POLYMERIZATION OF OLEFINS | MONTELL TECHNOLOGY COMPANY BV (NL) | 2000-05-11 | — | — | WO | disclosed |