Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.59 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.59 |
| ▸ | KMO | O15229 | 2/20 | 0.53 |
| ▸ | CYP2A6 | P11509 | 8/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | APP | P05067 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.50 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.50 |
| ▸ | HPGDS | O60760 | 1/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.49 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.49 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.49 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2722739 | 0.98 | MKNK1 (0.61) | MKNK1MKNK2KMOCYP2A6CYP3A4 | |
| SCHEMBL27790185 | 0.86 | MKNK1 (0.54) | MKNK1MKNK2KMOCYP2A6CYP3A4 | |
| SCHEMBL16102044 | 0.86 | KDR (0.54) | CYP3A4CYP2C9ALDH1A1HDAC4HDAC1 | |
| SCHEMBL13437383 | 0.84 | KDR (0.56) | CYP3A4CYP2C9ALDH1A1HDAC4HDAC1 | |
| SCHEMBL742466 | 0.83 | CSNK2A1 (0.46) | MKNK1MKNK2HDAC3HDAC4HDAC1 | |
| Lithium Ion SCHEMBL6737462 | 0.82 | MKNK1 (0.50) | MKNK1MKNK2KMOCYP2A6CYP3A4 | |
| SCHEMBL14496869 | 0.81 | CSNK2A1 (0.47) | MKNK1MKNK2HDAC3HDAC4HDAC1 | |
| SCHEMBL17201697 | 0.80 | ALDH1A1 (0.61) | MKNK1MKNK2CYP2A6CYP3A4CYP2C9 | |
| SCHEMBL17212188 | 0.79 | HCAR2 (0.43) | MKNK1MKNK2ALDH1A1GAAHCAR2 | |
| SCHEMBL21979546 | 0.77 | ALDH1A1 (0.47) | MKNK1MKNK2ALDH1A1GAAHPGDS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150373978-A1 | NOVEL HETEROCYCLIC COMPOUNDS AS PESTICIDES | BAYER IP GMBH (DE) | 2015-12-31 | — | — | US | disclosed |
| US-9173396-B2 | Heterocyclic compounds as pesticides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-11-03 | — | — | US | disclosed |
| US-20130261141-A1 | NOVEL HETEROCYCLIC COMPOUNDS AS PESTICIDES | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-10-03 | — | — | US | disclosed |
| US-6747023-B1 | INHIBITORS FOR ACTIVATED COAGULATION FACTOR X, COAGULATION SUPPRESSORS | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2004-06-08 | — | — | US | disclosed |
| US-20040082611-A1 | Anticoagulants; brain disorders; respiratory system disorders; side effect reduction | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2004-04-29 | — | — | US | disclosed |
| EP-1104754-A1 | NOVEL SULFONYL DERIVATIVES | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2001-06-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040082611-A1 | Anticoagulants; brain disorders; respiratory system disorders; side effect reduction | F2, CYC1, SULT2A1 | MKNK1 4210/4885MKNK2 4273/4885KMO 470/4885 |
| US-20130261141-A1 | NOVEL HETEROCYCLIC COMPOUNDS AS PESTICIDES | DDT, ACHE, PTMS | MKNK1 1428/4885MKNK2 1269/4885KMO 623/4885 |
| US-20150373978-A1 | NOVEL HETEROCYCLIC COMPOUNDS AS PESTICIDES | DDT, ACHE, PTMS | MKNK1 1428/4885MKNK2 1269/4885KMO 623/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.