Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 4/20 | 0.44 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.43 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.41 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.41 |
| ▸ | ESR1 | P03372 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL892160 | 0.90 | PTPN11 (0.42) | PTPN11MCHR1TLR8PTPN1PTPN6 | |
| SCHEMBL1776071 | 0.85 | PTPN11 (0.55) | PTPN11PTPN1PTPN6SMPD1ESR1 | |
| SCHEMBL28319408 | 0.85 | PTPN11 (0.55) | PTPN11PTPN1PTPN6SMPD1ESR1 | |
| SCHEMBL13957128 | 0.85 | PTPN11 (0.55) | PTPN11PTPN1PTPN6SMPD1ESR1 | |
| SCHEMBL2856448 | 0.85 | PTPN11 (0.55) | PTPN11PTPN1PTPN6SMPD1ESR1 | |
| SCHEMBL7620596 | 0.84 | PTPN11 (0.49) | PTPN11TLR8PTPN1PTPN6SMPD1 | |
| SCHEMBL17465202 | 0.84 | S1PR1 (0.45) | PTPN11PTPN1PTPN6SMPD1ESR1 | |
| SCHEMBL16266504 | 0.82 | PTPN11 (0.43) | PTPN11TLR8PTPN1PTPN6SMPD1 | |
| SCHEMBL8974024 | 0.78 | PTPN11 (0.57) | PTPN11TLR8PTPN1PTPN6 | |
| SCHEMBL8975125 | 0.77 | THRA (0.53) | PTPN11PTPN1PTPN6SMPD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6689290-B2 | Family of conducting liquid crystals | THE UNIVERSITY OF LEEDS (GB) | 2004-02-10 | — | — | US | claimed |
| US-20030160212-A1 | New family of conducting liquid crystals | UNIVERSITY OF LEEDS, THE (GB) | 2003-08-28 | — | — | US | claimed |
| US-6689290-B2 | Family of conducting liquid crystals | THE UNIVERSITY OF LEEDS (GB) | 2004-02-10 | — | — | US | disclosed |
| US-20030160212-A1 | New family of conducting liquid crystals | UNIVERSITY OF LEEDS, THE (GB) | 2003-08-28 | — | — | US | disclosed |
| EP-1240272-A2 | A NEW FAMILY OF CONDUCTING LIQUID CRYSTALS | THE UNIVERSITY OF LEEDS (GB) | 2002-09-18 | — | — | EP | disclosed |
| WO-2001042391-A2 | A NEW FAMILY OF CONDUCTING LIQUID CRYSTALS | UNIVERSITY OF LEEDS (GB) | 2001-06-14 | — | — | WO | disclosed |