Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.44 |
| ▸ | PDGFRB | P09619 | 4/20 | 0.42 |
| ▸ | KIT | P10721 | 1/20 | 0.42 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.42 |
| ▸ | FLT3 | P36888 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.41 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6739594 | 0.92 | KCNH2 (0.44) | L3MBTL1KCNH2GRIN2BPDGFRBKIT | |
| SCHEMBL6734803 | 0.91 | GRIN2B (0.54) | L3MBTL1KCNH2GRIN2BALDH1A1KDM4E | |
| SCHEMBL6739974 | 0.90 | KCNH2 (0.49) | L3MBTL1KCNH2GRIN2BSMN1; SMN2ALDH1A1 | |
| SCHEMBL6738037 | 0.87 | CHRNA7 (0.47) | L3MBTL1KCNH2ALDH1A1KDM4EMEN1 | |
| SCHEMBL6740165 | 0.86 | KCNH2 (0.46) | L3MBTL1NPSR1KCNH2GRIN2BALDH1A1 | |
| SCHEMBL6740324 | 0.86 | GRIN2B (0.52) | KCNH2GRIN2BALDH1A1KDM4EMEN1 | |
| SCHEMBL6742864 | 0.85 | KCNH2 (0.44) | NPSR1KCNH2SMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL6739331 | 0.85 | KCNH2 (0.46) | KCNH2GRIN2BPDGFRBSMN1; SMN2ALDH1A1 | |
| SCHEMBL6738896 | 0.85 | MEN1 (0.51) | L3MBTL1KCNH2GRIN2BALDH1A1KDM4E | |
| SCHEMBL6734967 | 0.84 | MEN1 (0.45) | KCNH2SMN1; SMN2ALDH1A1KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040229900-A1 | Bispidine compounds useful in the treatment of cardiac arrythmias | ASTRAZENECA AB (SE) | 2004-11-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040229900-A1 | Bispidine compounds useful in the treatment of cardiac arrythmias | ADRA1B, ADRB2, ADRA1D | L3MBTL1 1553/4885ATM 3568/4885NPSR1 120/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.