Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.40 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | SNCA | P37840 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | PLEC | Q15149 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6740056 | 0.88 | MAPT (0.46) | MAPTPOLBMAPK1PARP15PARP10 | |
| SCHEMBL6742068 | 0.85 | MAPT (0.50) | MAPTPOLBMAPK1PARP15PARP10 | |
| SCHEMBL6738712 | 0.85 | MAPT (0.46) | MAPTPOLBMAPK1PARP15PARP10 | |
| SCHEMBL6737674 | 0.83 | MAPT (0.43) | MAPTALDH1A1GAALMNAKMT2A | |
| SCHEMBL7601071 | 0.81 | CTSD (0.45) | MAPTPOLBMAPK1PARP15PARP10 | |
| SCHEMBL6741216 | 0.81 | LMNA (0.39) | MAPTPOLBMAPK1ALDH1A1GAA | |
| SCHEMBL6691257 | 0.80 | MAPT (0.52) | MAPTPOLBMAPK1PARP15PARP10 | |
| SCHEMBL7603075 | 0.79 | MAPT (0.46) | MAPTPOLBMAPK1PARP15PARP10 | |
| SCHEMBL7520130 | 0.78 | MAPT (0.51) | MAPTPOLBMAPK1PARP15PARP10 | |
| SCHEMBL7044465 | 0.71 | PDE4A (0.47) | MAPTALDH1A1GAALMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1185173-B1 | FUNGICIDAL COMBINATIONS | SYNGENTA PARTICIPATIONS AG (CH) | 2003-05-28 | — | — | EP | claimed |
| EP-0899255-B1 | Fungicidal 2,6,6'-trimethylbenzophenones | BASF AG (DE) | 2003-04-02 | — | — | EP | claimed |
| US-20020107246-A1 | Fungicidal combinations | SYNGENTA CROP PROTECTION, INC. | 2002-08-08 | — | — | US | claimed |
| EP-1185173-A1 | FUNGICIDAL COMBINATIONS | Syngenta Participations AG (CH) | 2002-03-13 | — | — | EP | claimed |
| WO-2000076317-A1 | FUNGICIDAL COMBINATIONS | SYNGENTA PARTICIPATIONS AG (CH) | 2000-12-21 | — | — | WO | claimed |
| EP-0899255-A2 | Fungicidal 2,6,6'-trimethylbenzophenones | American Cyanamid Company (US) | 1999-03-03 | — | — | EP | claimed |
| US-6790851-B2 | Fungicidal compositions | SYNGENTA CROP PROTECTION, INC. | 2004-09-14 | — | — | US | disclosed |
| US-6689776-B2 | APPLYING TO THE CROP PLANTS BEING INFESTED WITH FUNGAL DISEASE, A BIPHENOXY COMPOUND IN ASSOCIATION WITH STROBILURIN OR CYANOIMIDAZOLE, OR CARBONIC ACID AMIDE | SYNGENTA CROP PROTECTION, INC. | 2004-02-10 | — | — | US | disclosed |
| EP-1278414-B1 | FUNGICIDAL COMPOSITIONS | SYNGENTA PARTICIPATIONS AG (CH) | 2003-12-17 | — | — | EP | disclosed |
| US-20030166669-A1 | Fungicidal compositions | SYNGENTA CROP PROTECTION, INC. | 2003-09-04 | — | — | US | disclosed |
| EP-1185173-B1 | FUNGICIDAL COMBINATIONS | SYNGENTA PARTICIPATIONS AG (CH) | 2003-05-28 | — | — | EP | disclosed |
| EP-0899255-B1 | Fungicidal 2,6,6'-trimethylbenzophenones | BASF AG (DE) | 2003-04-02 | — | — | EP | disclosed |
| EP-1278414-A1 | FUNGICIDAL COMPOSITIONS | Syngenta Participations AG (CH) | 2003-01-29 | — | — | EP | disclosed |
| US-20020107246-A1 | Fungicidal combinations | SYNGENTA CROP PROTECTION, INC. | 2002-08-08 | — | — | US | disclosed |
| EP-1185173-A1 | FUNGICIDAL COMBINATIONS | Syngenta Participations AG (CH) | 2002-03-13 | — | — | EP | disclosed |
| WO-2001080643-A1 | FUNGICIDAL COMPOSITIONS | SYNGENTA PARTICIPATIONS AG (CH) | 2001-11-01 | — | — | WO | disclosed |
| WO-2000076317-A1 | FUNGICIDAL COMBINATIONS | SYNGENTA PARTICIPATIONS AG (CH) | 2000-12-21 | — | — | WO | disclosed |
| EP-0899255-A2 | Fungicidal 2,6,6'-trimethylbenzophenones | American Cyanamid Company (US) | 1999-03-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020107246-A1 | Fungicidal combinations | CBR1, CBR3, CYP4B1 | MAPT 4768/4885POLB 2925/4885MAPK1 1444/4885 |
| US-20030166669-A1 | Fungicidal compositions | CBR1, CBR3, CYP1B1 | MAPT 4860/4885POLB 2317/4885MAPK1 3159/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.