Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.46 |
| ▸ | MEN1 | O00255 | 8/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | GAA | P10253 | 4/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | PLEC | Q15149 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 5/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.42 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6738712 | 0.94 | MAPT (0.46) | MAPTMEN1KMT2AALDH1A1GAA | |
| SCHEMBL7600520 | 0.91 | MAPT (0.50) | MAPTMEN1KMT2AALDH1A1GAA | |
| SCHEMBL6740056 | 0.87 | MAPT (0.46) | MAPTMEN1KMT2AALDH1A1GAA | |
| SCHEMBL7520130 | 0.83 | MAPT (0.51) | MAPTMEN1KMT2AALDH1A1GAA | |
| SCHEMBL6691257 | 0.83 | MAPT (0.52) | MAPTMEN1KMT2AALDH1A1GAA | |
| SCHEMBL6742068 | 0.82 | MAPT (0.50) | MAPTMEN1KMT2AALDH1A1GAA | |
| Metrafenone SCHEMBL30013482 | 0.82 | ALDH1A1 (0.42) | MAPTMEN1KMT2AALDH1A1LMNA | |
| Metrafenone SCHEMBL29408434 | 0.82 | ALDH1A1 (0.42) | MAPTMEN1KMT2AALDH1A1LMNA | |
| Metrafenone SCHEMBL20788 | 0.82 | ALDH1A1 (0.42) | MAPTMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL7602501 | 0.81 | THRA (0.46) | MAPTMEN1KMT2AALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020155518-A1 | Method of detecting compounds that control fungal diseases via effects on sporulation | BASF AKTIENGESELLSCHAFT (DE) | 2002-10-24 | — | — | US | disclosed |