Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3A | P49840 | 6/20 | 0.58 |
| ▸ | GSK3B | P49841 | 6/20 | 0.58 |
| ▸ | PIM1 | P11309 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 3/20 | 0.48 |
| ▸ | RECQL | P46063 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | THRB | P10828 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13150780 | 0.81 | ALDH1A1 (0.70) | GSK3BPIM1ALDH1A1TDP1KMT2A | |
| SCHEMBL20339802 | 0.78 | GSK3B (0.63) | GSK3AGSK3BPIM1ALDH1A1TDP1 | |
| SCHEMBL20339669 | 0.78 | GSK3A (0.68) | GSK3AGSK3BPIM1ALDH1A1TDP1 | |
| SCHEMBL20339364 | 0.75 | GSK3A (0.59) | GSK3AGSK3BPIM1ALDH1A1TDP1 | |
| SCHEMBL3723533 | 0.74 | ALDH1A1 (0.43) | PIM1ALDH1A1TDP1KMT2ARECQL | |
| SCHEMBL5468543 | 0.74 | GSK3A (0.66) | GSK3AGSK3BALDH1A1TDP1KMT2A | |
| SCHEMBL20339642 | 0.73 | GSK3A (0.56) | GSK3AGSK3BPIM1ALDH1A1TDP1 | |
| SCHEMBL3176824 | 0.72 | PTGS1 (0.56) | GSK3AGSK3BALDH1A1TDP1KMT2A | |
| SCHEMBL11100770 | 0.71 | CA12 (0.58) | ALDH1A1TDP1KMT2AMEN1GAA | |
| SCHEMBL1519904 | 0.70 | GSK3A (0.56) | GSK3AGSK3BALDH1A1TDP1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040002526-A1 | Phospholipase D inhibitors and uses thereof | CELL THERAPEUTICS, INC. | 2004-01-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040002526-A1 | Phospholipase D inhibitors and uses thereof | PLD2, PLD1, PLA2G2D | GSK3A 2436/4885GSK3B 2077/4885PIM1 2212/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.