Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.62 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 4/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | HBB | P68871 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2615232 | 1.00 | LMNA (0.62) | LMNAMAPTTSHRTP53HTT | |
| Hydrochloric Acid SCHEMBL2771613 | 0.97 | LMNA (0.69) | LMNAMAPTTSHRTP53HTT | |
| Hydrochloric Acid SCHEMBL31671050 | 0.97 | LMNA (0.69) | LMNAMAPTTSHRTP53HTT | |
| SCHEMBL16590602 | 0.88 | — | — | |
| SCHEMBL17524417 | 0.87 | LMNA (0.48) | LMNAMAPTTSHRTP53HTT | |
| Methylene Chloride SCHEMBL6682460 | 0.86 | LMNA (0.41) | LMNAMAPTTSHRHRH3TDP1 | |
| SCHEMBL15800488 | 0.83 | LMNA (0.43) | LMNAMAPTHRH3MEN1KMT2A | |
| Chloromethane SCHEMBL9628755 | 0.82 | HRH3 (0.38) | LMNATSHRHRH3TDP1CYP2D6 | |
| SCHEMBL2729745 | 0.82 | HRH3 (0.41) | TSHRHRH3ALDH1A1CYP2D6NFKB1 | |
| SCHEMBL5358 | 0.82 | HRH3 (0.41) | TSHRHRH3ALDH1A1CYP2D6NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4169197-A | ANTIBIOTICS | THE UPJOHN COMPANY (US) | 1979-09-25 | — | — | US | claimed |
| US-20040127499-A1 | Compounds, compositions and methods for preventing and treating pestivirus infection and associated diseases | PEVEAR DANIEL C | 2004-07-01 | — | — | US | disclosed |
| US-6642231-B2 | Antineoplastic agents, treatment for neuronal injury and degeneration | AVENTIS PHARMACEUTICALS INC. | 2003-11-04 | — | — | US | disclosed |
| EP-1056744-B1 | 6,9-DISUBSTITUTED 2- TRANS-(4- AMINOCYCLOHEXYL) AMINO]PURINES | AVENTIS PHARMA INC (US) | 2003-10-22 | — | — | EP | disclosed |
| US-20030176431-A1 | Compounds, compositions and methods for preventing and treating pestivirus infection and associated diseases | PEVEAR DANIEL C | 2003-09-18 | — | — | US | disclosed |
| US-20030105098-A1 | 6,9-disubstituted 2-[trans-(4-aminocyclohexyl) amino] purines | AVENTISUB II INC. | 2003-06-05 | — | — | US | disclosed |
| EP-0921803-A4 | METHODS FOR PREVENTING AND TREATING PESTIVIRUS INFECTION AND ASSOCIATED DISEASES | VIROPHARMA INC (US) | 2003-04-02 | — | — | EP | disclosed |
| US-6541472-B1 | 3-thio-5H-1,2,4-triazino(5,6-b) indole derivatives | VIROPHARMA INCORPORATED | 2003-04-01 | — | — | US | disclosed |
| US-6479487-B1 | INHIBIT CYCLIN DEPENDENT KINASES, PARTICULARLY CDK-2; ANTIAPOPTOSIS AGENT; INHIBITS DEVELOPMENT OF NEOPLASMS | AVENTIS PHARMACEUTICALS INC. | 2002-11-12 | — | — | US | disclosed |
| EP-1056744-A1 | 6,9-DISUBSTITUTED 2- TRANS-(4- AMINOCYCLOHEXYL) AMINO]PURINES | Aventis Pharmaceuticals Inc. (US) | 2000-12-06 | — | — | EP | disclosed |
| EP-0214852-A2 | Perfluoroaminoethers | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1987-03-18 | — | — | EP | disclosed |
| US-4640930-A | CALCIUM CHANNEL BLOCKERS | HOFFMANN-LA ROCHE INC. (US) | 1987-02-03 | — | — | US | disclosed |
| US-4626877-A | RESIN LAYER CONTAINS A CATIONIC STARCH | KANZAKI PAPER MANUFACTURING COMPANY, LIMITED (JP) | 1986-12-02 | — | — | US | disclosed |
| EP-0179492-A2 | Heat-sensitive recording material | KANZAKI PAPER MANUFACTURING COMPANY LIMITED (JP) | 1986-04-30 | — | — | EP | disclosed |
| EP-0040793-B1 | NOVEL QUINAZOLINE-DIONE COMPOUNDS, PROCESS FOR PRODUCTION THEREOF AND PHARMACEUTICAL USE THEREOF | Ishikawa, Masayuki (JP) | 1985-08-28 | — | — | EP | disclosed |
| US-4405623-A | HYPOTENSIVE AGENTS, VASODILATORS | MASAYUKI ISHIKAWA (JP) | 1983-09-20 | — | — | US | disclosed |
| EP-0040793-A1 | Novel quinazoline-dione compounds, process for production thereof and pharmaceutical use thereof | Ishikawa, Masayuki (JP) | 1981-12-02 | — | — | EP | disclosed |
| US-4132709-A | [2]Benzopyrano[4,3-c]pyridine derivatives and process therefor | AYERST, MCKENNA & HARRISON, LTD. (CA) | 1979-01-02 | — | — | US | disclosed |
| US-4004008-A | ANTISPASMODIC, VASODILATION | ROTTA RESEARCH LABORATORIUM S.P.A. (IT) | 1977-01-18 | — | — | US | disclosed |
| US-4000275-A | BENZIMIDAZO(2,1-B) QUINAZOLIN-12(6H)ONES | ELI LILLY AND COMPANY (US) | 1976-12-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030105098-A1 | 6,9-disubstituted 2-[trans-(4-aminocyclohexyl) amino] purines | CDK6, CDK5, CDK2 | LMNA 2388/4885MAPT 2525/4885TSHR 4411/4885 |
| US-20030176431-A1 | Compounds, compositions and methods for preventing and treating pestivirus infection and associated diseases | ZC3HAV1, MAVS, HAVCR2 | LMNA 1813/4885MAPT 1994/4885TSHR 3786/4885 |
| US-20040127499-A1 | Compounds, compositions and methods for preventing and treating pestivirus infection and associated diseases | ZC3HAV1, MAVS, HAVCR2 | LMNA 1813/4885MAPT 1994/4885TSHR 3786/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.