Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 7/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 7/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.30 |
| ▸ | RELA | Q04206 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL674430 | 0.94 | SIGMAR1 (0.32) | SIGMAR1NPC1LMNATP53MAPT | |
| SCHEMBL673910 | 0.85 | MAPT (0.42) | SIGMAR1TBXAS1TP53MAPTSMN1; SMN2 | |
| SCHEMBL672956 | 0.79 | ALDH1A1 (0.44) | SIGMAR1TP53MAPTSMN1; SMN2 | |
| SCHEMBL2493417 | 0.69 | TSHR (0.42) | NPC1LMNATP53MAPTNFKB1 | |
| SCHEMBL10386799 | 0.68 | MEN1 (0.35) | KDM4ETDP1NPC1LMNATP53 | |
| Propylamine SCHEMBL28083663 | 0.68 | TP53 (0.47) | TDP1NPC1LMNATP53MAPT | |
| SCHEMBL5092012 | 0.68 | SIGMAR1 (0.51) | SIGMAR1TBXAS1 | |
| SCHEMBL674431 | 0.67 | ALDH1A1 (0.43) | ESR1ESR2KDM4ETDP1MAPT | |
| SCHEMBL335962 | 0.66 | MAPT (0.45) | KDM4ENPC1LMNATP53MAPT | |
| SCHEMBL3274550 | 0.66 | TP53 (0.36) | NPC1LMNATP53MAPTNFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1873168-B1 | MODIFIED CONJUGATED DIENE COPOLYMER, RUBBER COMPOSITIONS AND TIRES | BRIDGESTONE CORP (JP) | 2012-12-12 | — | — | EP | claimed |
| US-7968652-B2 | Modified conjugated diene copolymer, rubber compositions and tires | BRIDGESTONE CORPORATION (JP) | 2011-06-28 | — | — | US | claimed |
| US-7671136-B2 | Modified polymers prepared with lanthanide-based catalysts | BRIDGESTONE CORPORATION (JP) | 2010-03-02 | — | — | US | claimed |
| US-20090292043-A1 | MODIFIED CONJUGATED DIENE COPOLYMER, RUBBER COMPOSITIONS AND TIRES | BRIDGESTONE CORPORATION (JP) | 2009-11-26 | — | — | US | claimed |
| EP-1873168-A1 | MODIFIED CONJUGATED DIENE COPOLYMER, RUBBER COMPOSITIONS AND TIRES | Bridgestone Corporation (JP) | 2008-01-02 | — | — | EP | claimed |
| US-20060025539-A1 | Modified polymers prepared with lanthanide-based catalysts | OZAWA YOICHI | 2006-02-02 | — | — | US | claimed |
| US-6977281-B1 | Modified polymers prepared with lanthanide-based catalysts | BRIDGESTONE CORPORATION (JP) | 2005-12-20 | — | — | US | claimed |
| EP-1237935-A1 | MODIFIED POLYMERS PREPARED WITH LANTHANIDE-BASED CATALYSTS | Bridgestone Corporation (JP) | 2002-09-11 | — | — | EP | claimed |
| WO-2001034659-A1 | MODIFIED POLYMERS PREPARED WITH LANTHANIDE-BASED CATALYSTS | BRIDGESTONE CORPORATION (JP) | 2001-05-17 | — | — | WO | claimed |
| EP-1873168-B1 | MODIFIED CONJUGATED DIENE COPOLYMER, RUBBER COMPOSITIONS AND TIRES | BRIDGESTONE CORP (JP) | 2012-12-12 | — | — | EP | disclosed |
| US-7968652-B2 | Modified conjugated diene copolymer, rubber compositions and tires | BRIDGESTONE CORPORATION (JP) | 2011-06-28 | — | — | US | disclosed |
| US-7671136-B2 | Modified polymers prepared with lanthanide-based catalysts | BRIDGESTONE CORPORATION (JP) | 2010-03-02 | — | — | US | disclosed |
| US-20090292043-A1 | MODIFIED CONJUGATED DIENE COPOLYMER, RUBBER COMPOSITIONS AND TIRES | BRIDGESTONE CORPORATION (JP) | 2009-11-26 | — | — | US | disclosed |
| EP-1873168-A1 | MODIFIED CONJUGATED DIENE COPOLYMER, RUBBER COMPOSITIONS AND TIRES | Bridgestone Corporation (JP) | 2008-01-02 | — | — | EP | disclosed |
| EP-1237935-B1 | MODIFIED POLYMERS PREPARED WITH LANTHANIDE-BASED CATALYSTS | BRIDGESTONE CORP (JP) | 2007-01-24 | — | — | EP | disclosed |
| US-20060025539-A1 | Modified polymers prepared with lanthanide-based catalysts | OZAWA YOICHI | 2006-02-02 | — | — | US | disclosed |
| US-6977281-B1 | Modified polymers prepared with lanthanide-based catalysts | BRIDGESTONE CORPORATION (JP) | 2005-12-20 | — | — | US | disclosed |
| EP-1237935-A1 | MODIFIED POLYMERS PREPARED WITH LANTHANIDE-BASED CATALYSTS | Bridgestone Corporation (JP) | 2002-09-11 | — | — | EP | disclosed |
| WO-2001034659-A1 | MODIFIED POLYMERS PREPARED WITH LANTHANIDE-BASED CATALYSTS | BRIDGESTONE CORPORATION (JP) | 2001-05-17 | — | — | WO | disclosed |