Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 2/20 | 0.32 |
| ▸ | HRH1 | P35367 | 1/20 | 0.32 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.31 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.31 |
| ▸ | NEK2 | P51955 | 1/20 | 0.31 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.31 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.31 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL672956 | 0.94 | ALDH1A1 (0.44) | MAPTALDH1A1TP53GAATSHR | |
| SCHEMBL673982 | 0.85 | ESR1 (0.31) | MAPTTP53SMN1; SMN2SIGMAR1TBXAS1 | |
| SCHEMBL674430 | 0.79 | SIGMAR1 (0.32) | MAPTTP53SMN1; SMN2SIGMAR1 | |
| SCHEMBL5092012 | 0.70 | SIGMAR1 (0.51) | SIGMAR1TBXAS1 | |
| SCHEMBL5724891 | 0.65 | SLC6A1 (0.43) | MAOA | |
| SCHEMBL28537759 | 0.65 | GAA (0.62) | MAPTALDH1A1TP53GAATSHR | |
| SCHEMBL672957 | 0.65 | ALOX15 (0.44) | MAPTALDH1A1TP53TSHRHDAC3 | |
| SCHEMBL2491643 | 0.64 | MAPT (0.67) | MAPTALDH1A1TP53GAATSHR | |
| SCHEMBL8773365 | 0.62 | SIGMAR1 (0.42) | MAPTALDH1A1SIGMAR1MAOA | |
| SCHEMBL147847 | 0.62 | ALDH1A1 (0.69) | MAPTALDH1A1TP53GAATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1873168-B1 | MODIFIED CONJUGATED DIENE COPOLYMER, RUBBER COMPOSITIONS AND TIRES | BRIDGESTONE CORP (JP) | 2012-12-12 | — | — | EP | claimed |
| US-7968652-B2 | Modified conjugated diene copolymer, rubber compositions and tires | BRIDGESTONE CORPORATION (JP) | 2011-06-28 | — | — | US | claimed |
| US-7671136-B2 | Modified polymers prepared with lanthanide-based catalysts | BRIDGESTONE CORPORATION (JP) | 2010-03-02 | — | — | US | claimed |
| US-20090292043-A1 | MODIFIED CONJUGATED DIENE COPOLYMER, RUBBER COMPOSITIONS AND TIRES | BRIDGESTONE CORPORATION (JP) | 2009-11-26 | — | — | US | claimed |
| EP-1873168-A1 | MODIFIED CONJUGATED DIENE COPOLYMER, RUBBER COMPOSITIONS AND TIRES | Bridgestone Corporation (JP) | 2008-01-02 | — | — | EP | claimed |
| US-20060025539-A1 | Modified polymers prepared with lanthanide-based catalysts | OZAWA YOICHI | 2006-02-02 | — | — | US | claimed |
| US-6977281-B1 | Modified polymers prepared with lanthanide-based catalysts | BRIDGESTONE CORPORATION (JP) | 2005-12-20 | — | — | US | claimed |
| EP-1873168-B1 | MODIFIED CONJUGATED DIENE COPOLYMER, RUBBER COMPOSITIONS AND TIRES | BRIDGESTONE CORP (JP) | 2012-12-12 | — | — | EP | disclosed |
| US-7968652-B2 | Modified conjugated diene copolymer, rubber compositions and tires | BRIDGESTONE CORPORATION (JP) | 2011-06-28 | — | — | US | disclosed |
| US-7671136-B2 | Modified polymers prepared with lanthanide-based catalysts | BRIDGESTONE CORPORATION (JP) | 2010-03-02 | — | — | US | disclosed |
| US-20090292043-A1 | MODIFIED CONJUGATED DIENE COPOLYMER, RUBBER COMPOSITIONS AND TIRES | BRIDGESTONE CORPORATION (JP) | 2009-11-26 | — | — | US | disclosed |
| EP-1873168-A1 | MODIFIED CONJUGATED DIENE COPOLYMER, RUBBER COMPOSITIONS AND TIRES | Bridgestone Corporation (JP) | 2008-01-02 | — | — | EP | disclosed |
| EP-1237935-B1 | MODIFIED POLYMERS PREPARED WITH LANTHANIDE-BASED CATALYSTS | BRIDGESTONE CORP (JP) | 2007-01-24 | — | — | EP | disclosed |
| US-20060025539-A1 | Modified polymers prepared with lanthanide-based catalysts | OZAWA YOICHI | 2006-02-02 | — | — | US | disclosed |
| US-6977281-B1 | Modified polymers prepared with lanthanide-based catalysts | BRIDGESTONE CORPORATION (JP) | 2005-12-20 | — | — | US | disclosed |