SCHEMBL6740116

SCHEMBL6740116

CC(C)(NC(=O)[C@H](N)C(C)(C)S)C(=O)O

nearest known ligand 0.54

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.54
MAPT P10636 1/20 0.54
PTGS1 P23219 1/20 0.54
KDM4C Q9H3R0 1/20 0.36
DPP4 P27487 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL7756797 0.98 ALDH1A1 (0.52) ALDH1A1MAPTPTGS1KDM4CDPP4
Hydrochloric Acid SCHEMBL6733732 0.98 ALDH1A1 (0.52) ALDH1A1MAPTPTGS1KDM4CDPP4
SCHEMBL30811141 0.83 DPP4 (0.44) ALDH1A1MAPTPTGS1KDM4CDPP4
SCHEMBL1979304 0.77 KDM4C (0.39) ALDH1A1MAPTPTGS1KDM4CDPP4
SCHEMBL17690435 0.77 KDM4C (0.39) ALDH1A1MAPTPTGS1KDM4CDPP4
SCHEMBL8762973 0.74 ALDH1A1 (0.56) ALDH1A1MAPTPTGS1DPP4
SCHEMBL13655642 0.72 MAPT (0.43) ALDH1A1MAPTKDM4C
SCHEMBL31544617 0.72 KDM4C (0.40) ALDH1A1MAPTPTGS1KDM4C
SCHEMBL30811127 0.72 KDM4C (0.36) ALDH1A1MAPTPTGS1KDM4CDPP4
SCHEMBL29757439 0.72 KDM4C (0.44) ALDH1A1MAPTPTGS1KDM4CDPP4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6686336-B2 ALCOHOLISM THERAPY FEDERAL GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRES 2004-02-03 US claimed