Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | ACE | P12821 | 2/20 | 0.39 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | MME | P08473 | 1/20 | 0.30 |
| ▸ | CPA1 | P15085 | 1/20 | 0.30 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9911469 | 0.81 | KDM4C (0.42) | MAPTALDH1A1KDM4CTSHRPOLB | |
| SCHEMBL17690435 | 0.77 | KDM4C (0.39) | MAPTALDH1A1KDM4CTSHRPOLB | |
| SCHEMBL1979304 | 0.77 | KDM4C (0.39) | MAPTALDH1A1KDM4CTSHRPOLB | |
| SCHEMBL3883297 | 0.77 | KDM4C (0.39) | ALDH1A1KDM4CTSHRPOLB | |
| SCHEMBL13957176 | 0.77 | KDM4C (0.39) | ALDH1A1KDM4CTSHRPOLB | |
| SCHEMBL413295 | 0.74 | KDM4C (0.46) | ALDH1A1ACEKDM4CTSHRMME | |
| SCHEMBL6740116 | 0.72 | ALDH1A1 (0.54) | MAPTALDH1A1KDM4C | |
| SCHEMBL30811127 | 0.72 | KDM4C (0.36) | MAPTALDH1A1KDM4C | |
| SCHEMBL931001 | 0.71 | ACE (0.42) | MAPTALDH1A1LMNAPTGS2TDP1 | |
| SCHEMBL30811141 | 0.71 | DPP4 (0.44) | MAPTALDH1A1KDM4CTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1590387-B1 | RING-OPENED AZLACTONE INITIATORS FOR NITROXIDE-MEDIATED POLYMERIZATION | 3M INNOVATIVE PROPERTIES CO (US) | 2009-10-21 | — | — | EP | disclosed |