Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.56 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | MMP1 | P03956 | 2/20 | 0.31 |
| ▸ | MMP3 | P08254 | 1/20 | 0.31 |
| ▸ | MMP9 | P14780 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1174655 | 0.80 | DPP4 (0.50) | ALDH1A1MAPTPTGS1DPP4MMP1 | |
| SCHEMBL342534 | 0.80 | DPP4 (0.50) | ALDH1A1MAPTPTGS1DPP4MMP1 | |
| SCHEMBL343358 | 0.80 | DPP4 (0.50) | ALDH1A1MAPTPTGS1DPP4MMP1 | |
| Hydrochloric Acid SCHEMBL2005458 | 0.78 | DPP4 (0.48) | ALDH1A1MAPTPTGS1DPP4MMP1 | |
| SCHEMBL3416457 | 0.78 | SPHK1 (0.41) | ALDH1A1MAPTPTGS1DPP4 | |
| Hydrochloric Acid SCHEMBL2005453 | 0.78 | DPP4 (0.48) | ALDH1A1MAPTPTGS1DPP4MMP1 | |
| Hydrochloric Acid SCHEMBL20721188 | 0.78 | DPP4 (0.48) | ALDH1A1MAPTPTGS1DPP4MMP1 | |
| SCHEMBL22553488 | 0.77 | ALDH1A1 (0.52) | ALDH1A1MAPTPTGS1DPP4 | |
| SCHEMBL8202933 | 0.76 | MAPT (0.34) | ALDH1A1MAPTPTGS1DPP4 | |
| SCHEMBL12867478 | 0.76 | MAPT (0.34) | ALDH1A1MAPTPTGS1DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0784629-A1 | PEPTIDYL COMPOUNDS AND THEIR THERAPEUTIC USE AS INHIBITORS OF METALLOPROTEASES | Chiroscience Limited (GB) | 1997-07-23 | — | — | EP | disclosed |
| EP-0740655-A1 | METALLOPROTEINASE INHIBITORS | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 1996-11-06 | — | — | EP | disclosed |
| WO-1996011209-A1 | PEPTIDYL COMPOUNDS AND THEIR THERAPEUTIC USE AS INHIBITORS OF METALLOPROTEASES | CHIROSCIENCE LIMITED (GB) | 1996-04-18 | — | — | WO | disclosed |
| WO-1995019961-A1 | METALLOPROTEINASE INHIBITORS | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 1995-07-27 | — | — | WO | disclosed |