Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.33 |
| ▸ | CES2 | O00748 | 2/20 | 0.32 |
| ▸ | NOS3 | P29474 | 1/20 | 0.32 |
| ▸ | NOS1 | P29475 | 1/20 | 0.32 |
| ▸ | NOS2 | P35228 | 1/20 | 0.32 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.32 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.30 |
| ▸ | CDK9 | P50750 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5698477 | 0.80 | LMNA (0.42) | LMNACES2 | |
| SCHEMBL13370662 | 0.80 | NOS3 (0.35) | LMNACES2NOS3NOS1NOS2 | |
| SCHEMBL13248079 | 0.76 | LMNA (0.62) | LMNATRPV3CES2CCNT1CDK9 | |
| SCHEMBL12519550 | 0.76 | LMNA (0.38) | LMNATRPV3CES2 | |
| SCHEMBL9845773 | 0.76 | LMNA (0.34) | LMNACES2 | |
| SCHEMBL1255395 | 0.72 | CCNT1 (0.41) | TRPV3TBK1CCNT1CDK9 | |
| SCHEMBL24783009 | 0.72 | LMNA (0.40) | LMNATRPV3CES2 | |
| SCHEMBL12603760 | 0.72 | TRPV3 (0.38) | LMNATRPV3CES2CCNT1CDK9 | |
| SCHEMBL9392951 | 0.72 | DRD3 (0.44) | LMNATRPV3CES2 | |
| SCHEMBL20113146 | 0.71 | LMNA (0.35) | LMNATRPV3CES2CCNT1CDK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6686509-B2 | Process for producing α, α-difluorocycloalkane compound | MITSUI CHEMICALS, INC. (JP) | 2004-02-03 | — | — | US | disclosed |
| US-20030078460-A1 | Process for producing alpha, alpha-difluorocycloalkane compound | MITSUI CHEMICALS, INC. (JP) | 2003-04-24 | — | — | US | disclosed |