Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
| ▸ | MITF | O75030 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | FCGR3B | O75015 | 1/20 | 0.30 |
| ▸ | FCGR1A | P12314 | 1/20 | 0.30 |
| ▸ | FCGR2A | P12318 | 1/20 | 0.30 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6743356 | 0.90 | MITF (0.35) | KDM4EALDH1A1ALOX5GAAMAPT | |
| SCHEMBL6272601 | 0.83 | MITF (0.33) | MITFADRA2B | |
| SCHEMBL6739441 | 0.82 | ADRA2B (0.34) | ADRA2B | |
| Hydrochloric Acid SCHEMBL6740843 | 0.82 | PRSS1 (0.33) | MAPTMITFADRA2B | |
| SCHEMBL6739905 | 0.78 | EGFR (0.38) | KDM4EALDH1A1MAPTMITFCA2 | |
| SCHEMBL6735813 | 0.78 | ADRA2B (0.35) | FCGR3BFCGR1AFCGR2AADRA2B | |
| SCHEMBL6737786 | 0.77 | CA12 (0.32) | SIRT1CA2 | |
| SCHEMBL6741719 | 0.77 | CA12 (0.38) | KDM4EALDH1A1GAAMAPTSIRT1 | |
| SCHEMBL6735144 | 0.76 | SLC6A2 (0.37) | ALDH1A1MAPTSLC6A2SLC6A4CA2 | |
| SCHEMBL6739725 | 0.76 | ADRA2B (0.37) | ALDH1A1MAPTFCGR3BFCGR1AFCGR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6685751-B2 | SUCH AS 2-((2-AMINO-PHENYLAMINO)-METHYL)-1,4-DIAMINOBENZENE; HAIR DYES | WELLA AKTIENGESELLSCHAFT (DE) | 2004-02-03 | — | — | US | disclosed |
| US-6602302-B1 | Mixtures of carbocyclic amines such as 2-((2-aminophenylamino) -methyl)-1,4-diaminobenzene, couplers and developers, having photostability, wash and colorfastness, used for dyeing human hair | WELLA AG (DE) | 2003-08-05 | — | — | US | disclosed |
| US-20030110578-A1 | Substituted 1,4-diaminobenzene compounds and oxidation dye precursor compositions containing same | WELLA INTERNATIONAL OPERATIONS SWITZERLAND SARL (CH) | 2003-06-19 | — | — | US | disclosed |
| EP-1108708-B1 | 1,4-Diaminobenzene derivatives and colouring agents containing these compounds | WELLA AG (DE) | 2003-01-08 | — | — | EP | disclosed |
| EP-1108708-A1 | 1,4-Diaminobenzene derivatives and colouring agents containing these compounds | Wella Aktiengesellschaft (DE) | 2001-06-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030110578-A1 | Substituted 1,4-diaminobenzene compounds and oxidation dye precursor compositions containing same | KRT18, AOC1, DAO | KDM4E 1123/4885ALDH1A1 43/4885ALOX5 1432/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.