SCHEMBL6740222

SCHEMBL6740222

O=C1CC1CSc1ccccc1

nearest known ligand 0.56

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CRBN Q96SW2 7/20 0.56
ALDH1A1 P00352 3/20 0.44
MAPK1 P28482 1/20 0.44
FFAR1 O14842 1/20 0.42
NPC1 O15118 5/20 0.39
RAB9A P51151 5/20 0.39
KMT2A Q03164 2/20 0.38
LMNA P02545 1/20 0.38
MAPT P10636 1/20 0.38
CYP3A4 P08684 2/20 0.38
CYP1A2 P05177 1/20 0.38
CYP2D6 P10635 1/20 0.38
CYP2C19 P33261 1/20 0.38
CASP3 P42574 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
SENP8 Q96LD8 1/20 0.38
SENP7 Q9BQF6 1/20 0.38
SENP6 Q9GZR1 1/20 0.38
CYB5R3 P00387 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5709685 0.80 CRBN (0.56) CRBNALDH1A1MAPK1NPC1RAB9A
SCHEMBL5709651 0.78 CRBN (0.55) CRBNALDH1A1NPC1RAB9AKMT2A
SCHEMBL6968272 0.75 CRBN (0.51) CRBNALDH1A1MAPK1FFAR1NPC1
SCHEMBL6960972 0.75 CRBN (0.51) CRBNALDH1A1MAPK1FFAR1NPC1
SCHEMBL4394602 0.72 CRBN (1.00) CRBN
SCHEMBL2665515 0.71 ALDH1A1 (0.50) CRBNALDH1A1MAPK1FFAR1NPC1
SCHEMBL8758609 0.71 CRBN (0.48) CRBNALDH1A1NPC1RAB9AKMT2A
SCHEMBL6966938 0.69 ITGB1 (0.42) CRBNALDH1A1FFAR1NPC1RAB9A
SCHEMBL5513100 0.68 DRD4 (0.47) CRBNALDH1A1MAPK1FFAR1NPC1
SCHEMBL1778553 0.68 ALDH1A1 (0.46) CRBNALDH1A1MAPK1FFAR1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6692893-B2 ONIUM SALTS OF ARYLSULFONYLOXYNAPHTHALENESULFONATE ANIONS WITH IODONIUM OR SULFONIUM CATIONS; USE IN DEEP ULTRAVIOLET LITHOGRAPHY SHIN-ETSU CHEMICAL CO., LTD. (JP) 2004-02-17 US disclosed
US-6416928-B1 HALOGENONIUM OR SULFONIUM SALTS OF SULFONATED DIPHENYLALKANE SHIN-ETSU CHEMICAL CO., LTD. (JP) 2002-07-09 US disclosed
US-20020076643-A1 Novel onium salts, photoacid generators, resist compositions, and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2002-06-20 US disclosed
US-20020077493-A1 Novel onium salts, photoacid generators, resist compositions, and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2002-06-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020077493-A1 Novel onium salts, photoacid generators, resist compositions, and patterning process ABL1, PI4K2B, FES CRBN 3111/4885ALDH1A1 4358/4885MAPK1 96/4885
US-20020076643-A1 Novel onium salts, photoacid generators, resist compositions, and patterning process PNN, PI4K2B, PI4K2A CRBN 2725/4885ALDH1A1 4218/4885MAPK1 143/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.