Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 3/20 | 0.42 |
| ▸ | ITGA5 | P08648 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.39 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.38 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.38 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6970938 | 0.79 | KMT2A (0.42) | ITGB1ITGA5ALDH1A1KMT2ACRBN | |
| SCHEMBL7386119 | 0.76 | ITGB1 (0.51) | ITGB1ITGA5NPC1ALDH1A1KMT2A | |
| SCHEMBL6967927 | 0.75 | ITGB1 (0.37) | ITGB1ITGA5MAPTITGA4RIPK1 | |
| SCHEMBL6967928 | 0.75 | ITGB1 (0.37) | ITGB1ITGA5MAPTITGA4RIPK1 | |
| SCHEMBL7386171 | 0.73 | AGTR2 (0.44) | NPC1ALDH1A1FFAR1LMNAMAPT | |
| SCHEMBL7379702 | 0.73 | AGTR2 (0.44) | NPC1ALDH1A1FFAR1LMNAMAPT | |
| SCHEMBL6689324 | 0.71 | CA12 (0.47) | ITGB1ITGA5ALDH1A1MAPTKMT2A | |
| SCHEMBL7561265 | 0.70 | ITGB1 (0.41) | ITGB1ITGA5ITGA4RIPK1 | |
| SCHEMBL6740222 | 0.69 | CRBN (0.56) | NPC1ALDH1A1FFAR1LMNAMAPT | |
| SCHEMBL8439418 | 0.67 | SIGMAR1 (0.40) | ITGB1ITGA5FFAR1KMT2AITGA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1023265-B1 | AZETIDINONE DERIVATIVES FOR THE TREATMENT OF HCMV INFECTIONS | BOEHRINGER INGELHEIM CA LTD (CA) | 2003-01-15 | — | — | EP | disclosed |
| US-6211170-B1 | Azetidinone derivatives for the treatment of HCMV infections | BOEHRINGER INGELHEIM (CANADA) LTD. (CA) | 2001-04-03 | — | — | US | disclosed |