SCHEMBL6740235

SCHEMBL6740235

CC(C)(C)OC(=O)CCCCS

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FOLH1 Q04609 3/20 0.44
EPHX2 P34913 1/20 0.41
HDAC1 Q13547 5/20 0.37
HDAC6 Q9UBN7 4/20 0.37
HDAC2 Q92769 3/20 0.37
HDAC4 P56524 3/20 0.36
HDAC8 Q9BY41 3/20 0.36
TSHR P16473 1/20 0.36
HDAC3 O15379 2/20 0.34
DGKA P23743 1/20 0.33
RECQL P46063 1/20 0.33
STING1 Q86WV6 1/20 0.33
TDP1 Q9NUW8 1/20 0.32
CYP2D6 P10635 1/20 0.32
DNM1 Q05193 1/20 0.32
HDAC7 Q8WUI4 1/20 0.32
HDAC10 Q969S8 1/20 0.32
HDAC11 Q96DB2 1/20 0.32
HDAC9 Q9UKV0 1/20 0.32
HDAC5 Q9UQL6 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2676200 0.98 EPHX2 (0.43) FOLH1EPHX2HDAC1HDAC6HDAC2
SCHEMBL6738496 0.93 EPHX2 (0.39) FOLH1EPHX2HDAC1HDAC6HDAC2
SCHEMBL134923 0.89 EPHX2 (0.46) EPHX2HDAC1HDAC6HDAC2HDAC8
SCHEMBL14482131 0.86 EPHX2 (0.49) EPHX2HDAC1HDAC6HDAC2HDAC8
SCHEMBL20450540 0.86 EPHX2 (0.49) EPHX2HDAC1HDAC6HDAC2HDAC8
SCHEMBL2380206 0.86 EPHX2 (0.49) EPHX2HDAC1HDAC6HDAC2HDAC8
SCHEMBL14482719 0.86 EPHX2 (0.49) EPHX2HDAC1HDAC6HDAC2HDAC8
SCHEMBL3914424 0.86 EPHX2 (0.49) EPHX2HDAC1HDAC6HDAC2HDAC8
SCHEMBL3251209 0.86 EPHX2 (0.49) EPHX2HDAC1HDAC6HDAC2HDAC8
SCHEMBL28924668 0.86 EPHX2 (0.49) EPHX2HDAC1HDAC6HDAC2HDAC8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4700124-A2 OLIGONUCLEOTIDE-LIGAND CONJUGATES AND PROCESS FOR THEIR PREPARATION Alnylam Pharmaceuticals, Inc. (US) 2026-02-25 EP disclosed
US-20250075208-A1 OLIGONUCLEOTIDE-LIGAND CONJUGATES AND PROCESS FOR THEIR PREPARATION BANK OF AMERICA, N.A. 2025-03-06 US disclosed
US-12173288-B2 Oligonucleotide-ligand conjugates and process for their preparation ALNYLAM PHARMACEUTICALS, INC. (US) 2024-12-24 US disclosed
US-20220348914-A1 OLIGONUCLEOTIDE-LIGAND CONJUGATES AND PROCESS FOR THEIR PREPARATION BANK OF AMERICA, N.A. 2022-11-03 US disclosed
EP-4039278-A1 OLIGONUCLEOTIDE-LIGAND CONJUGATES AND PROCESS FOR THEIR PREPARATION Alnylam Pharmaceuticals, Inc. (US) 2022-08-10 EP disclosed
EP-3019200-B1 OLIGONUCLEOTIDE-LIGAND CONJUGATES AND PROCESS FOR THEIR PREPARATION ALNYLAM PHARMACEUTICALS INC (US) 2022-03-23 EP disclosed
US-10808246-B2 Oligonucleotide-ligand conjugates and process for their preparation ALNYLAM PHARMACEUTICALS, INC. (US) 2020-10-20 US disclosed
US-20170183297-A1 OMEGA-3 ANALOGUES THE UNIVERSITY OF SYDNEY (AU) 2017-06-29 US disclosed
US-20160376585-A1 OLIGONUCLEOTIDE-LIGAND CONJUGATES AND PROCESS FOR THEIR PREPARATION BANK OF AMERICA, N.A. 2016-12-29 US disclosed
US-20160376585-A1 OLIGONUCLEOTIDE-LIGAND CONJUGATES AND PROCESS FOR THEIR PREPARATION BANK OF AMERICA, N.A. 2016-12-29 US disclosed
EP-2628744-B1 Silicon-containing surface modifier, resist underlayer film composition containing this, and patterning process SHINETSU CHEMICAL CO (JP) 2016-11-30 EP disclosed
EP-3019200-A2 OLIGONUCLEOTIDE-LIGAND CONJUGATES AND PROCESS FOR THEIR PREPARATION Alnylam Pharmaceuticals, Inc. (US) 2016-05-18 EP disclosed
WO-2015006740-A2 OLIGONUCLEOTIDE-LIGAND CONJUGATES AND PROCESS FOR THEIR PREPARATION ALNYLAM PHARMACEUTICALS, INC. (US) 2015-01-15 WO disclosed
WO-2015006740-A2 OLIGONUCLEOTIDE-LIGAND CONJUGATES AND PROCESS FOR THEIR PREPARATION ALNYLAM PHARMACEUTICALS, INC. (US) 2015-01-15 WO disclosed
US-20040043903-A1 Herbicides; applying to plants BASF AKTIENGESELLSCHAFT (DE) 2004-03-04 US disclosed
US-20040023807-A1 3-Arylisothiazoles and their use as herbicides BASF AKTIENGESELLSCHAFT (DE) 2004-02-05 US disclosed
US-20030216257-A1 1-aryl-4-alkyl halide-2(1h)-pyridones and their use as herbicides BASF AKTIENGESELLSCHAFT (DE) 2003-11-20 US disclosed
EP-1289970-A1 3-ARYLISOTHIAZOLES AND THEIR USE AS HERBICIDES BASF AKTIENGESELLSCHAFT (DE) 2003-03-12 EP disclosed
WO-2001087863-A1 3-ARYLISOTHIAZOLES AND THEIR USE AS HERBICIDES BASF AKTIENGESELLSCHAFT (DE) 2001-11-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160376585-A1 OLIGONUCLEOTIDE-LIGAND CONJUGATES AND PROCESS FOR THEIR PREPARATION IGF2R, IRS1, INSR FOLH1 412/4885EPHX2 3762/4885HDAC1 2062/4885
US-10808246-B2 Oligonucleotide-ligand conjugates and process for their preparation RTCB, IGF2BP2, SNRPE FOLH1 1650/4885EPHX2 3949/4885HDAC1 2170/4885
US-20040023807-A1 3-Arylisothiazoles and their use as herbicides DDT, HAX1, SULT1E1 FOLH1 3506/4885EPHX2 2749/4885HDAC1 1926/4885
US-20220348914-A1 OLIGONUCLEOTIDE-LIGAND CONJUGATES AND PROCESS FOR THEIR PREPARATION IGF2R, IRS1, INSR FOLH1 412/4885EPHX2 3762/4885HDAC1 2062/4885
US-12173288-B2 Oligonucleotide-ligand conjugates and process for their preparation IGF2R, IRS1, INSR FOLH1 412/4885EPHX2 3762/4885HDAC1 2062/4885
US-20040043903-A1 Herbicides; applying to plants DDT, DRD1, DRD4 FOLH1 2440/4885EPHX2 1056/4885HDAC1 2604/4885
US-20170183297-A1 OMEGA-3 ANALOGUES ELOVL3, PTGER3, PTGES3 FOLH1 672/4885EPHX2 679/4885HDAC1 3777/4885
US-20250075208-A1 OLIGONUCLEOTIDE-LIGAND CONJUGATES AND PROCESS FOR THEIR PREPARATION IGF2R, IRS1, INSR FOLH1 412/4885EPHX2 3762/4885HDAC1 2062/4885
US-20030216257-A1 1-aryl-4-alkyl halide-2(1h)-pyridones and their use as herbicides CYP1B1, DDT, CYP1A1 FOLH1 4009/4885EPHX2 1207/4885HDAC1 923/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.