Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.65 |
| ▸ | APP | P05067 | 2/20 | 0.50 |
| ▸ | CYP1A1 | P04798 | 5/20 | 0.48 |
| ▸ | CYP1B1 | Q16678 | 5/20 | 0.48 |
| ▸ | ABL1 | P00519 | 2/20 | 0.44 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.44 |
| ▸ | BCR | P11274 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP2E1 | P05181 | 2/20 | 0.42 |
| ▸ | CYP2C8 | P10632 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | CYP4B1 | P13584 | 2/20 | 0.42 |
| ▸ | CYP2B6 | P20813 | 2/20 | 0.42 |
| ▸ | CYP3A5 | P20815 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16140275 | 0.88 | ALDH1A1 (0.50) | ALDH1A1APPCYP1A1CYP1B1ABL1 | |
| SCHEMBL673820 | 0.88 | APP (0.69) | ALDH1A1APPCYP1A1CYP1B1ABL1 | |
| SCHEMBL8006347 | 0.87 | ALDH1A1 (0.55) | ALDH1A1APPCYP1A1CYP1B1ABL1 | |
| SCHEMBL1005880 | 0.84 | APP (0.77) | ALDH1A1APPCYP1A1CYP1B1ABL1 | |
| SCHEMBL712263 | 0.82 | APP (0.52) | ALDH1A1APPCYP1A1CYP1B1ABL1 | |
| SCHEMBL23583704 | 0.81 | ALDH1A1 (0.48) | ALDH1A1APPCYP1A1CYP1B1ABL1 | |
| SCHEMBL673173 | 0.81 | ALDH1A1 (0.48) | ALDH1A1APPCYP1A1CYP1B1ABL1 | |
| SCHEMBL21252661 | 0.81 | ALDH1A1 (0.48) | ALDH1A1APPCYP1A1CYP1B1ABL1 | |
| 1,3,5-Trimethoxybenzene SCHEMBL28493 | 0.80 | ALDH1A1 (1.00) | ALDH1A1CYP1A1CYP1B1ABL1ABCB1 | |
| SCHEMBL11475256 | 0.80 | ALDH1A1 (0.61) | ALDH1A1APPCYP1A1CYP1B1ABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113754619-B | Method for preparing polysubstituted benzofuran-4-formic acid compound under catalysis of ruthenium | 广州大学 | 2022-12-20 | — | — | CN | disclosed |
| US-20220296538-A1 | Substituted Tolans for the Modulation of Microbial Colonization | BioMendics, LLC (US) | 2022-09-22 | — | — | US | disclosed |
| US-11351126-B2 | Substituted tolans for the modulation of microbial colonization | BioMendics, LLC (US) | 2022-06-07 | — | — | US | disclosed |
| CN-113754619-A | Method for preparing polysubstituted benzofuran-4-formic acid compound under catalysis of ruthenium | 广州大学 | 2021-12-07 | — | — | CN | disclosed |
| US-9263683-B2 | Use of cobalt complexes for preparing an active layer in a photovoltaic cell, and corresponding photovoltaic cell | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2016-02-16 | — | — | US | disclosed |
| EP-2691404-B1 | USE OF COBALT COMPLEXES FOR THE PREPARATION OF THE ACTIVE LAYER OF A PHOTVOLTAIC CELL, AND CORRESPONDING PHOTOVOLTAIC CELL | CENTRE NAT RECH SCIENT (FR) | 2015-05-06 | — | — | EP | disclosed |
| EP-2691404-B1 | USE OF COBALT COMPLEXES FOR THE PREPARATION OF THE ACTIVE LAYER OF A PHOTVOLTAIC CELL, AND CORRESPONDING PHOTOVOLTAIC CELL | CENTRE NAT RECH SCIENT (FR) | 2015-05-06 | — | — | EP | disclosed |
| US-20140290745-A1 | USE OF COBALT COMPLEXES FOR PREPARING AN ACTIVE LAYER IN A PHOTOVOLTAIC CELL, AND CORRESPONDING PHOTOVOLTAIC CELL | UNIVERSITE PIERRE ET MARIE CURIE (PARIS 6) (FR) | 2014-10-02 | — | — | US | disclosed |
| US-20140290745-A1 | USE OF COBALT COMPLEXES FOR PREPARING AN ACTIVE LAYER IN A PHOTOVOLTAIC CELL, AND CORRESPONDING PHOTOVOLTAIC CELL | UNIVERSITE PIERRE ET MARIE CURIE (PARIS 6) (FR) | 2014-10-02 | — | — | US | disclosed |
| US-8716355-B2 | Hydroxylated tolans and related compounds in the treatment of a cancer | KENT STATE UNIVERSITY (US) | 2014-05-06 | — | — | US | disclosed |
| US-20110160301-A1 | ASCORBATE, VITAMIN K3 AND HYDROXYTOLANS IN THE TREATMENT OF CANCER | KENT STATE UNIVERSITY (US) | 2011-06-30 | — | — | US | disclosed |
| US-20110130468-A1 | HYDROXYLATED TOLANS AND RELATED COMPOUNDS IN THE TREATMENT OF A CANCER | KENT STATE UNIVERSITY (US) | 2011-06-02 | — | — | US | disclosed |
| WO-2009126700-A1 | HYDROXYLATED TOLANS AND RELATED COMPOUNDS AS COSMETICS OR THERAPEUTICS FOR SKIN CONDITIONS | KENT STATE UNIVERSITY (US) | 2009-10-15 | — | — | WO | disclosed |
| US-20090069569-A1 | CYCLOADDITION OF AZIDES AND ALKYNES | INSTITUT CATALA D'INVESTIGACIO QUIMICA (ES) | 2009-03-12 | — | — | US | disclosed |
| WO-2008157745-A1 | ASCORBATE, VITAMIN K3 AND HYDROXYTOLANS IN THE TREATMENT OF CANCER | KENT STATE UNIVERSITY (US) | 2008-12-24 | — | — | WO | disclosed |
| WO-2008157787-A2 | HYDROXYLATED TOLANS AND RELATED COMPOUNDS IN THE TREATMENT OF CANCER | KENT STATE UNIVERSITY (US) | 2008-12-24 | — | — | WO | disclosed |
| US-7094809-B2 | Topical administration of dihydroxytoluene to block viral replication | NORTHEASTERN OHIO UNIVERSITIES COLLEGE OF MEDICINE (US) | 2006-08-22 | — | — | US | disclosed |
| US-20030203974-A1 | Methods for treating subjects infected with herpes virus or Neisseria gonorrheae | DOCHERTY JOHN (US) | 2003-10-30 | — | — | US | disclosed |
| US-6599945-B2 | Administering a hydroxylated tolan to the host cell of a patient having or suspected having an infection induced by herpes virus | NORTHEASTERN OHIO UNIVERSITIES COLLEGE OF MEDICINE | 2003-07-29 | — | — | US | disclosed |
| US-20020103262-A1 | Methods for treating subjects infected with a herpes virus or neisseria gonorrheae | KENT STATE UNIVERSITY | 2002-08-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11351126-B2 | Substituted tolans for the modulation of microbial colonization | LMAN1, DPM1, DSTN | ALDH1A1 1348/4885APP 3466/4885CYP1A1 333/4885 |
| US-20220296538-A1 | Substituted Tolans for the Modulation of Microbial Colonization | LMAN1, DPM1, DSTN | ALDH1A1 1348/4885APP 3466/4885CYP1A1 333/4885 |
| US-20110130468-A1 | HYDROXYLATED TOLANS AND RELATED COMPOUNDS IN THE TREATMENT OF A CANCER | TKT, HAAO, TTPA | ALDH1A1 134/4885APP 4407/4885CYP1A1 387/4885 |
| US-20110160301-A1 | ASCORBATE, VITAMIN K3 AND HYDROXYTOLANS IN THE TREATMENT OF CANCER | PROC, VKORC1L1, VKORC1 | ALDH1A1 630/4885APP 4756/4885CYP1A1 964/4885 |
| US-20090069569-A1 | CYCLOADDITION OF AZIDES AND ALKYNES | PF4, AFF4, FLI1 | ALDH1A1 540/4885APP 4258/4885CYP1A1 175/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.